Papers

Accurate assessment of tumor proportion score (TPS) in non-small cell lung cancer (NSCLC) is critical for treatment planning and prognosis. Key challenges include the tedious manual work required to annotate each slide, combined with the limited number of experts certified for this task. Multiple instance learning (MIL) has proven to be an effective approach for predicting TPS scores at the slide level; however, existing methods struggle with non-expressive (zero class) images. Our approach involves two models: (1) an embedding-extraction and multiclass-classification network that captures the histopathological features of individual patches, and (2) a MIL model that aggregates these embeddings to predict zero-inflated beta (ZIBeta) parameters representing the overall TPS probability distribution for the entire slide. Using only slide-level TPS scores as labels, we demonstrate how this end-to-end framework can leverage a novel distribution-based architecture to improve prediction accuracy and explainability. ZIBeta modeling significantly outperforms baseline linear and ridge regression while capturing expected accuracy through distribution concentration.

Reward models for Reinforcement Learning from Human Feedback (RLHF) pool preferences across thousands of annotators and fit one global affine calibrator, collapsing raters with systematically different rating-scale offsets and slopes into a single average-rater fit that does not match any individual annotator. PEBS is a per-rater empirical-Bayes shrinkage estimator: it fits per-rater affine calibrators on a held-out slice of each annotator's ratings and applies Morris-James-Stein empirical-Bayes shrinkage toward the population mean, in closed form and without retraining the reward model. On PRISM, PEBS reduces within-user held-out RMSE by 8.58% over the pooled population-slope baseline. The procedure replicates on PluriHarms harm ratings (Qwen-2.5 base, in-family) with a +9.66% RMSE reduction over the same population-slope baseline. PEBS is a closed-form post-hoc estimator for annotator-specific affine calibration in RLHF reward modeling; it leaves the reward base model unchanged and estimates only the rater-level map used at inference time for new ratings.

This paper formulates frame-level freeway risk assessment as a multi-agent scene graph-level binary classification problem, where each video or trajectory frame is labeled risky if any TTC- or PET-based conflict violates a specified severity threshold. We construct a relation-aware graph per frame with vehicles as nodes and two interaction types as edges: same-lane (longitudinal) and adjacent-lane (lateral), augmented with physics-informed edge features aligned to rear-end and lane-change conflict mechanisms. Building on a structured benchmarking suite of non-graph models and graph baselines, we propose HIA-GAT, a dual-stream heterogeneous graph attention network that processes longitudinal and lateral interactions through dedicated attention pathways and fuses them via a conflict-type-aware gating mechanism with event-level gate supervision derived from SSM conflict attribution. Experiments on the NGSIM I-80 and US-101 freeway datasets across nine TTC and PET threshold configurations show that HIA-GAT achieves the best average risk-ranking performance (AUC 0.835 on I-80 and 0.867 on US-101), with the largest gains on PET-only (lane-change) settings where relational structure is essential. Beyond accuracy, the learned gate provides interpretable per-vehicle attribution of dominant conflict type, supporting actionable, real-time freeway safety monitoring. We show that graph structure is critical for modeling lateral conflict risk, while longitudinal risk can often be captured by non-relational aggregation.

Prompt injection is the top security risk for LLM-integrated applications, yet every defense proposed so far has been broken. We prove this is not a coincidence: in shared-embedding architectures that lack enforced control-data separation, perfect prompt-injection prevention is mathematically impossible. We formalize prompted systems as Prompted Action Models whose outputs include control-authoritative actions: refusal decisions, tool authorization, policy routing, and memory writes. We define Semantic-Faithful Control (SFC), the property that such behavior depends only on the meaning of untrusted input, not on how it is encoded. We then prove SFC is unachievable within the shared pipeline, via three results: a provenance-recovery impossibility (shared representations make trusted and untrusted content statistically inseparable, bounded by total variation distance); control-path exposure (untrusted tokens enter control-relevant computation through the same attention value-aggregation that determines outputs); and a finite-coverage invariance gap (finite training cannot certify invariance over infinite semantic-equivalence classes). We ground each quantity in measurements on production tokenizers and models. The result is structural, not a gap in current defenses. It mirrors the code-data confusion in Von Neumann machines that gives rise to buffer overflows, a vulnerability class that took decades of layered defenses (DEP, Write-XOR-Execute, ASLR, stack canaries, and ultimately memory-safe languages) to contain, because no single mechanism sufficed. The implication is the same: prompt injection cannot be eliminated by better in-pipeline classification or alignment alone. It requires architectural separation of instruction and data channels. We identify the root cause and the class of solution it demands.

Social media popularity prediction aims to forecast the future reach or influence of online content from early-stage observations. Accurate prediction enables key downstream applications, such as advertising optimization and strategic content planning by users, creators, and platforms. Despite substantial progress, existing popularity prediction works often fail to jointly consider multimodal content and temporal social interaction signals. Moreover, the literature remains highly fragmented across datasets, modalities, observation windows, prediction targets, and evaluation protocols. This fragmentation prevents fair comparison and obscures a systematic understanding of how textual, visual, temporal, and interaction-based signals jointly shape popularity dynamics. To address these challenges, we introduce MMG-Pop, a Multi-modal Graph-based Popularity Prediction benchmark, which unifies datasets, modalities, temporal interaction signals, and representative baselines under a standardized evaluation protocol. Furthermore, we propose MMG-PopNet, a unified multi-modal graph-based network that jointly models the aforementioned multi-modal signals and graph-structured social interactions. Extensive experiments on MMG-Pop, comprising four datasets across Bluesky and Reddit platforms, demonstrate the superior performance of MMG-PopNet and yield new insights into cross-platform training generalization, multi-task prediction benefits, multi-modality contributions, and LLM prediction limitation. These findings establish a unified foundation for future research on social dynamics modeling and intervention under heterogeneous modalities and socially-aware agentic ecosystem paradigms.

We introduce the context-ready transformer, a new recurrent neural network architecture built from a D-layer transformer block that pre-contextualizes each token before it enters the block. During left-to-right generation, a correction network combines the previous position's block output – a cached summary of past context – with the current token embedding, so the tokenenters the block already contextualized rather than as a raw embedding. At sequential inference, the correction chain makes the architecture a recurrent neural network. For training, we unroll the correction process K times over the full sequence, processing all positions in parallel at each step. A pretrained transformer can also be converted to a context-ready model by adding a zero-initialized correction FFN and fine-tuning. We evaluate across widths, depths, block sizes, and two datasets, with all comparisons against standard transformers, variants, and ablations. A D=5 model beats a 12-layer transformer while generating 1.7x faster on an A100. With K=10, a single-layermodel (D=1) beats a 6-layer transformer with a 2.6x inference speedup, and sequential inference matches parallel K=10 to within 0.01 PPL. The architecture benefits most from wide representations and long contexts. On a pointer-chasing task, D=1 trained with BPTT solves all 10 composition levels, while standard transformers exhibit staircase-like depth dependence.

Large Language Models (LLMs) possess broad conceptual knowledge acquired through large-scale text pretraining, yet their potential to supervise models in other modalities remains underexplored. In this work, we propose LaViD–Language-to-Visual Knowledge Distillation–a simple and effective framework for transferring high-level semantic knowledge from a language-only teacher to a vision-only student model. Instead of relying on paired multimodal data, LaViD elicits conceptual signals from an LLM by prompting it to generate multiple-choice questions (MCQs) that probe semantic distinctions between visual classes. Each class is mapped to a soft label distribution over these MCQs, forming a rich conceptual signature that guides the student through an auxiliary distillation loss. Notably, despite using a language-only teacher without access to image data, LaViD consistently outperforms recent methods like MaKD that distill from vision-language models across multiple fine-grained benchmarks. It also achieves competitive or superior performance compared to state-of-the-art visual distillation methods such as DKD and MLKD, with further gains when combined with logit standardization. On the Waterbirds dataset, LaViD substantially improves worst-group accuracy, demonstrating enhanced robustness to spurious correlations with distillation. Code is available at https://github.com/lliangthomas/lavid.

Agent benchmarks for measuring memory largely study textual cases, in which information is deliberately extracted from the environment, written down, and then later retrieved. In other words, they assess what agents elected to record, not what they happened to see. We introduce DMV-Bench (code: https://github.com/yyyujintang/DMV-Bench), the first interactive benchmark for visual memory in multimodal agents, to study this often-neglected property. DMV-Bench is built on (1) a controlled home-furnishing e-commerce environment, supported by a catalog of 1,000 product variants, and (2) a text-leakage contract which ensures that the primary discriminative signal of each task is solely in the pixels. In DMV-Bench, agents undergo chains of autonomous shopping sessions in which every visited product image carries a unique, pre-rendered incidental cue that the agent is later asked to recall. We show that conventional solutions struggle with this task. Inspired by dual-coding theory, we propose a memory architecture that uses parallel visual and verbal codes, which we call DualMem. On DMV-Bench, DualMem outperforms a caption-only baseline and three recent multimodal agent-memory systems across multi-session chain lengths on multiple models. These gains persist even adjusting for memory-bank size and encoding-position bias. Further experiments also reveal an asymmetric division of labor between the two codes; a weighted coding scheme is often strongest. We view this as a step towards memory systems that preserve a richer record of agents' observations.

Large language model (LLM) agents have demonstrated strong capability in sequential decision-making, yet they remains fundamentally reactive in long-horizon tasks. Unlike humans who employ "what-if" reasoning to evaluate potential plans before commitment, standard agents lack an internal world model to simulate future outcomes. Therefore, we propose to internalize future-aware planning by training a single autoregressive model to verbalize both a prospective state rollout and a plan-conditioned success estimate-a textual analogue of the Q-value. Crucially, we identify a format-capability gap: simply fine-tuning agents on look-ahead traces during post-training leads to superficial mimicry of foresight without genuine predictive grounding. To bridge this gap, we introduce a three-stage training paradigm: (i) World Model Agentic Mid-Training (WM-AMT) to inject latent predictive capabilities into the policy; (ii) Format-Eliciting SFT (FE-SFT) to structure this injected capability; and (iii) Foresight-Conditioned Reinforcement Learning (FC-RL) to refine the calibration and utility of the generated simulations. Evaluated on search and mathematical reasoning tasks, our approach consistently outperforms other training baselines. Our results demonstrate that effective internal world modeling in LLM agents requires a capability-first training pipeline to achieve grounded and calibrated foresight.

How should we evaluate generation systems that combine autoregressive (AR) and diffusion decoding? We study this question through Speculative Refinement (SpecRef), a training-free hybrid method that warm-starts a masked diffusion language model from an AR draft using entropy-guided selective masking. Evaluating SpecRef across six benchmarks (HumanEval, MBPP, GSM8K, BBH, ARC-Challenge, HellaSwag) with three distinct evaluation protocols (execution-based pass@1, exact-match, log-likelihood scoring), we surface several findings relevant beyond our specific system: (1) code benchmarks conflate structural discovery with logical correctness: providing a syntactic scaffold lifts accuracy from near zero to over 20% without changing the model, indicating that much of the baseline failure is structural; (2) a refinement tension phenomenon where multi-stage correction degrades already-correct tokens, exposing benchmark saturation ceilings invisible to single-model evaluation; (3) log-likelihood and generative evaluation produce different model rankings for the same model pair, suggesting they measure different capabilities; (4) standard Python post-processing silently breaks code evaluation for non-AR generators. These observations apply to any multi-stage or non-autoregressive generation pipeline and point toward more diagnostic evaluation practices.

Large language model (LLM) agents operate over long, multi-session interactions in which facts change: a user moves, a price updates, a plan is revised. Acting correctly requires using the current value of a fact and discarding values that have been superseded. We isolate this ability on real conversational data and show that it is a distinct, unsolved failure. On the knowledge-update subset of LongMemEval, replacing an agent's full context with a bounded, self-maintained memory drops accuracy from 92% to 77% even on a frontier model (gpt-5.4), a gap that is statistically significant (paired McNemar p<0.005) and persists across model scale while full-context accuracy saturates near 92%. The bottleneck is therefore memory maintenance, not comprehension, and is not closed by a stronger model. We then ask whether this is merely an undersized memory, and find it is not: as the conversation grows 24x, accuracy falls further (from 68% to 28%), and granting the agent proportionally more memory yields no detectable recovery (28% to 28%, n=25). The failure scales with the length of the conversation, not the compression ratio. We release Supersede, an open reinforcement-learning environment (on the verifiers / prime-rl stack) that turns this measurement into a training signal: agents are rewarded for answering from the current value and penalized for stale ones. Finally, we close the loop and show the gap is trainable: GRPO fine-tuning a small open model (Qwen2.5-3B) on this environment nearly doubles its held-out supersession accuracy on real, unseen conversations (9.0% to 16.7%, a single run), along a monotonic checkpoint curve indicating the learned policy, not the harness, carries the gain. To our knowledge this is the first trainable environment whose reward targets temporal fact-currency, and the first evidence the supersession gap can be trained down, not only measured.

Personality prompting shapes how large language models communicate, yet whether these behavioral shifts affect objective task outcomes remains under-explored. Prior work shows that agents prompted with low agreeableness produce adversarial language, while those prompted with high agreeableness become cooperative, but the relationship between communication style and task performance has not been systematically examined across multiple domains. In this work, we investigate whether personality composition matters for multi-agent team performance by manipulating personality traits across frontier LLMs on three task domains: structured coding, open-ended research collaboration, and competitive bargaining. We find that personality effects depend critically on task structure. In coding tasks, low agreeableness leads to large communication shifts that have little effect on milestone completion. In open-ended collaboration and bargaining, the same manipulation substantially degrades performance. We discuss implications for multi-agent system design and the limits of personality manipulation.

Understanding which genes control which traits in an organism remains one of the central challenges in biology. Despite significant advances in data collection technology, our ability to map genes to traits is still limited. This genome-to-phenome (G2P) challenge spans several problem domains, including plant breeding, and requires methods capable of reasoning over high-dimensional, heterogeneous, and biologically structured data. Current datasets and data repositories, however, are not well-equipped for this task. Current studies do not link gene expression and trait data, and most focus on very specific traits, limiting the breadth of possible correlations. To address this gap, we present the novel Gene-Graph Regression for Arabidopsis Functional Traits (GRAFT) dataset, a curated multi-modal dataset linking gene expression profiles with phenotypic trait measurements in Arabidopsis thaliana, a model organism in plant biology. GRAFT supports tasks such as phenotype prediction and interpretable graph learning. In addition, we benchmark conventional regression and explanatory baselines, including a biologically-informed hypergraph baseline, to validate gene-trait associations. To the best of our knowledge, this is the first dataset to provide multimodal gene information and heterogeneous trait or phenotype data for the same Arabidopsis thaliana specimens. With GRAFT, we aim to foster research to accurately understand the relationship between genotypes and phenotypes using gene information, higher-order gene pairings, and trait data from multiple sources.

3D Scene Graph Generation (3DSGG) represents 3D scenes as structured object–relation–object graphs for spatial understanding. In observer-centric spatial perception, the same scene may be expressed under different local observer frames while its structure remains unchanged. However, existing models typically assume a fixed scene-aligned reference frame and may produce semantically inconsistent predictions when the scene is re-expressed in another observer frame. We attribute this failure to the heterogeneous frame dependency of relational predicates. Directional predicates such as $\textit{left}$, $\textit{front}$, $\textit{right}$, and $\textit{behind}$ are $\textbf{Observer-Dependent Relations}$, whereas most contact, support, and semantic predicates, such as $\textit{standing on}$ and $\textit{attached to}$, are approximately $\textbf{Observer-Independent Relations}$. Conventional models do not distinguish these frame responses, leading to degraded relation prediction under observer-frame reorientation. We introduce $\textbf{Observer-Aware Relations (OAR)}$, which combines observer-aware geometric encoding and relation specialization, supported by frame-stable object encoding, for unified multi-label predicate prediction. Experiments on 3DSSG show that OAR consistently outperforms baselines across controlled observer-frame reorientations without training-time frame-reorientation augmentation, while remaining competitive on the standard benchmark. The project page is available at https://oar-predicate.github.io/.

We study a quantum autoencoder (QAE) for compression-driven anomaly detection in brain MRI data. The approach leverages angle encoding to map image patches into quantum states, followed by a variational encoder-decoder architecture trained to discard information via auxiliary trash qubits. Anomaly scores reflect the degree to which inputs resist compression relative to normal data, with higher scores corresponding to deviations from the learned normal manifold. Evaluated on publicly available brain MRI DICOM datasets, the method achieves a slice-level ROC-AUC of approximately 0.95 and a patch-level ROC-AUC of approximately 0.813, outperforming classical autoencoder and PCA baselines. Analysis of the learned parameters reveals a pronounced encoder-decoder asymmetry, where effective anomaly detection arises from structured information compression within the encoder rather than increased parameter magnitude or decoder expressivity. This results in a controlled compression-reconstruction trade-off with a clear operating regime that supports principled threshold selection. Qualitative evaluation further shows that the QAE produces spatially localized anomaly heatmaps aligned with tumorous regions. The results, supported by promising baseline performances, demonstrate that quantum autoencoders provide an interpretable and controllable mechanism for anomaly detection based on incompressibility with respect to a learned latent representation. This work highlights the potential of quantum autoencoders as a principled tool for studying compression dynamics in quantum machine learning, with promising implications for decision support in medical imaging workflows.

Software engineering, whether performed by humans or by AI agents, requires reasoning about how software behaves. We call the internal model that supports such reasoning the software world model, and view current code-execution benchmarks as covering one well-studied slice of it – control flow. In this paper, we take a step toward a broader evaluation by shifting the observable axis to execution resources: alongside test outcome and exception class, we predict peak memory, wall-clock time, and ranked profiler outputs at method and line granularity. We use SWE-bench Verified as the source of data to hold the test close to real-world software engineering tasks. All tested models, frontier ones included, show modest performance and brittle behaviour, suggesting a notable lack of understanding of how software is executed, as opposed to how its source code is written.

Deep learning has shown significant potential in medical image analysis, particularly for disease detection using MRI scans. Accurate and early diagnosis of brain tumors remains challenging due to the complexity of brain structures and reliance on manual interpretation. This work presents an automated deep learning-based approach for brain tumor detection from MRI images using Convolutional Neural Networks and Residual Networks. Transfer learning is applied with two pretrained architectures, ResNet18 and ResNet50, to classify MRI scans into tumor and non-tumor categories. Experiments are conducted on a dataset of 3,929 brain MRI images, evaluating the impact of model depth and fine-tuning strategies. The results show that ResNet18 achieves a higher accuracy of 97% compared to 96% for ResNet50, demonstrating better generalization on limited medical data. The proposed framework enables fast, accurate, and cost-effective brain tumor detection, supporting early diagnosis and clinical decision-making.

Efficient sampling of molecular systems at thermodynamic equilibrium is a hallmark challenge in statistical physics. This challenge has driven the development of Boltzmann Generators (BGs), which allow rapid generation of uncorrelated equilibrium samples by combining a generative model with exact likelihoods and an importance sampling correction. However, modern BGs predominantly rely on normalizing flows (NFs), which either suffer from limited expressivity due to strict invertibility constraints (discrete time) or computationally expensive likelihoods (continuous time). In this paper, we propose Autoregressive Boltzmann Generators (ArBG) – a novel autoregressive modelling framework – that overcomes these limitations by departing from the flow-based BG paradigm. ArBG circumvents the topological constraints of flows and enables sequential inference-time interventions, while offering enhanced scalability by leveraging architectures effective in Large Language Models. We empirically demonstrate that ArBG leads to significant improvements over flow-based models across all benchmarks, but particularly in larger peptide systems such as the 10-residue Chignolin. Furthermore, we introduce Robin, a 132 million parameter transferable model trained with the ArBG framework which improves over the previous state-of-the-art, reducing the zero-shot energy error, E-W$_2$, on 8-residue systems by over 60$\%$. The code can be found at the following link: https://github.com/danyalrehman/autobg.

Neural surrogate models offer fast approximate mappings from PDE parameters to solutions, but they typically treat solving as a purely statistical task: once trained, they struggle to correct their own constraint violations and extrapolate beyond the training distribution. Recent hybrid methods promote physical correctness by targeting the PDE residual via gradient descent or Gauss–Newton steps, but inherit the compute cost and instability of the underlying classical optimizers. We show, theoretically and empirically, that numerically minimizing the PDE residual can be an unreliable proxy for reconstruction accuracy in ill-conditioned systems, explaining why these methods often do not make accurate predictions despite achieving low residuals. We propose error-conditioned Neural Solvers (ENS), built on a different principle: rather than an optimization target, the PDE residual field is passed as a direct input to the network at each iteration, enabling it to read the spatial structure of its own errors and learn an update policy to iteratively correct its predictions. Across four PDE families, ENS attains the highest prediction accuracy in the large majority of settings, with gains reaching $10\times$ on turbulent Kolmogorov flow, while avoiding the expensive compute cost of hybrid methods. ENS's learned correction policy generalizes under distribution shift, including zero-shot parameter changes and cross-equation transfer, where its relative advantage is largest in the ill-conditioned regimes where residual minimization is least reliable. Project website: https://neuralsolver.github.io/.

Entity Matching (EM) is a core operation in the data integration pipeline, where records from different sources are compared to determine whether they refer to the same real-world entity. Recent work has incorporated domain information and low-resource learning techniques to better adapt EM systems to realistic settings. While these approaches have demonstrated strong performance, it remains unclear how they behave under varying data constraints and levels of supervision in practice. In this paper, we investigate a state-of-the-art method for low-resource, domain-aware EM–BEACON–and study how its performance is affected by different algorithmic choices and data availability conditions. We conduct a series of targeted experiments to evaluate these variations, providing deeper insight into the role of distribution alignment and the behavior of the BEACON framework.

Digital twins have emerged as a promising paradigm for personalized healthcare, enabling modeling of individual behavior and health trajectories. In cognitive health, early detection of Mild Cognitive Impairment (MCI) remains challenging, where language and conversational patterns serve as non-invasive biomarkers. In this work, we propose a language-based digital twin framework that leverages large language models (LLMs) to mimic the conversational behavior of elderly individuals by incorporating stylometric cues and contextual metadata. To evaluate fidelity and cognitive consistency, we introduce a multi-head conditional variational autoencoder (cVAE) that jointly measures reconstruction quality and predicts cognitive scores. Experiments on the I-CONECT dataset show that the digital twin preserves identity-specific characteristics and achieves reconstruction and MoCA prediction errors comparable to real data, while outperforming baseline GPT-generated responses. These results highlight the potential of language-based digital twins as a scalable and non-invasive approach for personalized and continuous cognitive health monitoring.

Multimodal web agents can assist humans in operating repetitive GUI tasks, where effective task planning is essential for decomposing complex tasks into executable actions. While small open source MLLMs are cost efficient and privacy preserving compared with commercial large models, they suffer from weak planning and limited cross website generalization. To address these limitations, we introduce the planning experience exploration and utilization (PEEU) method, which autonomously explores environments to discover experiences and utilizes hindsight experience to synthesize strictly aligned, high level training data. To quantitatively analyze the generalization behaviors driving this performance, we propose the task decomposition hierarchical analysis framework (TDHAF) to systematically study compositional generalization across three task granularities: low, middle and high levels. Our analysis reveals that mastering low level atomic skills does not guarantee high level planning competence, while high level task training yields stronger OOD generalization. Experiments on real world benchmarks demonstrate PEEU's superior effectiveness: our 7B model achieves 30.6% accuracy, outperforming the much larger Qwen2.5-VL-32B model. These demonstrate constructing hindsight high level tasks and leveraging experiences is crucial for OOD planning abilities of small MLLMs.

Sparse autoencoders (SAEs) have become a leading tool for interpreting the representations of vision foundation models, decomposing their polysemantic activations into a larger set of sparse, more monosemantic features. The Top-$k$ SAE, a now-standard variant, enforces sparsity architecturally through its activation function, retaining only the $k$ most active latents per input. Because it was designed precisely to avoid the $\ell_1$ penalty used by earlier SAEs and its known drawbacks, it has not been combined with an explicit sparsity regularizer. Yet the Top-$k$ SAE retains limitations of its own, and we hypothesize that a sparsity penalty acting before the selection could sharpen each latent's selectivity and make the code more interpretable, without reintroducing the drawbacks of the $\ell_1$ penalty. We introduce two sparsity regularizers compatible with the Top-$k$ architecture, both acting on the activations before the Top-$k$ selection: an $\ell_1$ penalty on the unselected (off-support) units, and a scale-invariant $\ell_1/\ell_2$-ratio penalty that concentrates the code onto fewer effective units. Both penalties are applied only to the batch-active units, those selected by the Top-$k$ operator at least once within the batch. Across two datasets, three vision foundation models, and a range of $k$, both regularizers consistently improve monosemanticity at no cost to reconstruction quality. The $\ell_1/\ell_2$ penalty further concentrates information into fewer latents, making reconstruction more robust to the inference-time choice of $k$ and improving small-budget linear probing. Our central finding is that hard architectural sparsity and soft sparsity regularization are complementary rather than mutually exclusive.

AI healthcare chatbots are increasingly used to support health information seeking and self-management, yet their performance and impact on users remains to be studied. This study examines over 15,000 user reviews from 59 AI healthcare chatbot apps to explore how these systems function in everyday informational and emotional contexts. Topic modeling and interpretive analysis identify three recurring breakdowns: access barriers and service unreliability, user experience and interaction quality, and billing and customer support issues. Privacy and security concerns are associated with the most negative experiences. By framing AI healthcare chatbots as information infrastructures, our findings highlight how failures in access, usability, and trust affect users, offering actionable insights for designers, policymakers, and information professionals aiming to improve digital health systems.

Multi-model LLM systems such as routing, voting, cascades, fusion, and mixture-of-agents are used to beat single-model accuracy. We show that their gain is capped by a quantity the field rarely reports. For any policy whose output is one member model answer, accuracy cannot exceed one minus beta, where beta is the rate at which every model is wrong on the same query. In contrast, the usual diagnostic, average pairwise error correlation rho, cannot identify beta: error laws with identical marginals and pairwise correlations can have different all-wrong rates. A Clopper-Pearson bound on beta gives a finite-sample certificate on the largest gain any router, vote, or cascade could deliver before training a router. Across 67 models from 21 providers, a tetrachoric-calibrated single-factor model still underprices the all-wrong tail: on open-ended mathematics, observed beta is 0.052 versus 0.023 under the full 67-model Gaussian copula, about 2.5 times underpricing, with 90 percent CI 1.7 to 3.4 and k equals 17. The effect recurs on execution-graded code, where beta is 0.079. Re-asking the same GPQA-Diamond questions in free-response rather than multiple-choice form reopens the tail, with beta 0.127 and a five-judge panel with kappa 0.73 to 0.92, locating co-failure in answer format rather than subject. At matched quality, low-rho heterogeneous ensembles beat high-rho Self-MoA, but on checkable tasks in our pool, combining models rarely beats the single best model without a strong query-level routing signal. Gains come from models failing on different questions, not from adding more models.

Large language models (LLMs) are increasingly used to screen and rank job applicants, creating incentives for candidates to strategically manipulate algorithmic hiring systems. We study prompt injection in automated résumé screening, defined as subtle self-promotional text that introduces no new qualifications but is designed to influence LLM evaluations. Using controlled experiments, we show that prompt injection reliably improves applicant rankings when résumé quality is homogeneous and few candidates inject. However, its effectiveness rapidly diminishes as more candidates inject, collapsing when manipulation becomes widespread. When candidate quality is heterogeneous, prompt injection is less effective on average, but can occasionally allow lower-quality candidates to outrank higher-quality ones, raising fairness concerns. Overall, LLM-based screening is most vulnerable when manipulation is rare and candidate quality differences are small. Code and resources are publicly available at: https://github.com/preetb1199/Prompt_Injection_ACL26

Mechanistic epidemiological models are widely used to support infectious disease forecasting and public-health decision making. Bayesian calibration of such models is commonly performed using Markov chain Monte Carlo (MCMC), which can become computationally expensive for high-dimensional nonlinear systems and repeated near-real-time analyses. Here, we investigate simulation-based inference (SBI) using neural posterior estimation as a scalable alternative for Bayesian calibration of a mechanistic SECIR epidemiological model using COVID-19 intensive care unit (ICU) occupancy data from Germany during 2020. We compared SBI and MCMC across multiple epidemic phases using both 31-day inference windows and a substantially more challenging 201-day reconstruction problem involving multiple transmission change points. Posterior agreement was evaluated quantitatively using Wasserstein distances and Kullback-Leibler divergences together with posterior predictive checks. Across the 31-day windows, SBI recovered posterior distributions in strong agreement with MCMC while accurately reproducing observed ICU trajectories. In the 201-day setting, SBI preserved the dominant posterior structure despite increased uncertainty. SBI, by combining CPU and GPU resources, substantially reduced computational runtime compared with MCMC, which was restricted to running on CPUs. Whereas MCMC required approximately 1000 seconds for the 31-day inference problems, SBI achieved comparable posterior and predictive performance in approximately 60-70 seconds on a single GPU. For the 201-day inference problem, SBI required an average of 157 seconds, while the MCMC runs took over 19,000 seconds. Our results demonstrate that SBI provides a rapid and computationally efficient framework for Bayesian calibration of mechanistic epidemiological models, supporting repeated near-real-time inference and rapid outbreak analysis.

Earth Observation (EO) forecasting aims to predict future Earth surface dynamics from satellite observations under changing meteorological conditions. In this paper, we view this task as a partially observed, weather-driven world modeling problem, in which weather acts as a conditioning signal, while forecasting remains uncertain due to sparse observations and unobserved land-surface states. However, existing methods do not fully capture this setting: deterministic models collapse uncertainty into a single future prediction, while diffusion-based methods typically treat weather variables as undifferentiated conditioning signals, and existing benchmarks focus mainly on reconstruction accuracy rather than whether forecasts respond correctly to changed weather forcing.We introduce EO-WM, a video diffusion transformer for multispectral EO forecasting. EO-WM incorporates a physically informed conditioning framework that represents meteorological forcing through a climatological baseline, weather anomalies, and cumulative physical stress signals. Specifically, it separates baseline and anomaly through distinct conditioning pathways, and accumulates anomalous forcing over time to capture sustained heat and drought stress. To evaluate weather-response behavior beyond standard metrics, we introduce two diagnostic benchmarks: an Extreme Summer Benchmark for severity-aware prediction of vegetation degradation under extreme weather, and a Seasonal Matched-Pair Benchmark for testing response fidelity under changed weather forcing. Experiments show that EO-WM reduces the error in predicted Normalized Difference Vegetation Index (NDVI) decline amplitude by a relative 5.63% and improves directional hit rate by a relative 7.80%, while remaining competitive on standard pixel-level metrics. The benchmarks and model will be made open-source at https://github.com/Luo-Z13/EO-WM.

Recently, a few works have made early attempts to study test-time scaling for embodied tasks. However, two major challenges remain unsolved: (1) reasoning can effectively improve the performance of the policy, but its scaling mechanism has seldom been studied; (2) historical information is essential, as embodied tasks are inherently long-horizon and sequential, making sole reliance on current observations for action scaling inadequate due to the lack of historical context utilization. To address these challenges, we introduce E-TTS, a modular and plug-and-play Embodied Test-Time Scaling framework that unifies reasoning and action scaling for robotic manipulation via history-aware iterative refinement with vision-language verifiers. To support joint reasoning-action scaling, E-TTS performs reasoning-action joint sampling and scoring in a pairwise manner. To better utilize historical information, E-TTS uses a history buffer to store historical context, which is then used by reasoning and action verifiers to evaluate the sampled candidates. Unlike conventional open-loop TTS methods, E-TTS introduces feedback generation into the sampling process to form a closed-loop iterative refinement mechanism, enhancing both inference efficiency and environmental adaptability. Each component functions as an independent and composable module, allowing flexible and adaptive configuration depending on task requirements. To evaluate the advantages of our framework, we conduct experiments across 4 different benchmarks, 6 environments, 3 embodiments, and 4 base vision-language-action models. The experimental results demonstrate that, without requiring additional expert data collection or retraining, E-TTS consistently improves performance, achieving up to a 33.14% increase in simulation and 26.62% in real-world scenarios.

Building persistent embodied agents in unstructured environments demands unified orchestration of heterogeneous tools spanning both cyber (APIs, IoT) and physical (manipulation, navigation) domains, coupled with autonomous recovery from physical failures that inevitably arise over extended operation. Existing systems treat these as separate problems: VLM-based planners lack a unified cyber-physical action space, agent frameworks accumulate unbounded context that degrades temporal coherence, and VLA policies execute open-loop without detecting their own failures. We argue that persistent autonomy requires not a monolithic model but a hierarchical asynchronous architecture with explicit separation of planning, memory, and verification. To this end, we present OmniAct, a framework integrating a multimodal semantic planner for skill routing across unified action spaces, an adaptive hierarchical memory with event-boundary-driven compression for sub-linear context growth, and an asynchronous visual preemption engine that closes the semantic loop during physical execution. Across 40 real-world long-horizon tasks on two robotic platforms coordinating four IoT devices, OmniAct achieves consistent improvements in end-to-end success across all complexity levels, maintains near-flat token consumption over under 100k+ accumulated interaction tokens, and elevates mid-scale open-weight models to proprietary-level performance.