Computer Vision · Cross-listed from cs.GR
Real-Time AttentionBender: Granular Interactive Network Bending of Video Diffusion Transformers
Adam Cole, Rebecca Fiebrink and Mick Grierson
Generative
video models have achieved remarkable visual fidelity, yet their
prompt-only interface offers thin creative agency and obscures the model's material process from the artists working with it. We present Real-Time AttentionBender, a tool that extends the practice of network bending across the full depth of the
video diffusion transformer (DiT) and brings it into live, interactive generation. Built as a plugin within the DayDream Scope ecosystem and wrapping open-source real-time Wan pipelines, the tool exposes self-
attention, cross-
attention, and the feed-forward network as independently manipulable surfaces, with targeting down to individual
diffusion steps, DiT layers,
prompt tokens, and hidden
neurons. The immediacy of live manipulation affords what we call "material intimacy" with the model: a responsive, near-mechanistic feel for how specific layers and
neurons shape generated
video. We position the tool as simultaneously an XAIxArts probe into
transformer internals and an expressive instrument for discovering aesthetics outside the model's default representational space.
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Computer Vision · Cross-listed from cs.MM
BRITE: A Benchmark for Reliable and Interpretable T2V Evaluation on Implausible Scenarios
Advait Tilak, Jiwon Choi, Nazifa Mouli et al. (+1 more)
The rapid advancement of photorealistic Text-to-
Video (T2V) generation brings in an urgent need for up-to-date evaluation methods. Existing
benchmarks largely overlooked implausible scenarios and do not measure audio-visual
alignment. We introduce BRITE, the first framework that unifies (1) implausible prompting, (2) fine-grained assessment of audio-visual consistency, and (3) QA-based interpretable evaluation into a comprehensive T2V
benchmark. Unlike fully automated
Multimodal LLM-based pipelines, which are prone to
hallucination and
prompt ambiguity, BRITE guarantees reliability through a rigorous human-in-the-loop protocol for
benchmark creation. Evaluating five state-of-the-art models (Sora 2, Veo 3.1, Runway Gen4.5, Pixverse V5.5, and Qwen3Max), we reveal a critical performance gap: while models excel at static object composition, they exhibit significant degradation in object-action binding and audio-visual synchronization. Our framework offers the community a reliable, interpretable
benchmark and evaluation framework that can detect and locate limitations in the next generation of T2V models, especially for off-
manifold prompts
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All authors Advait Tilak, Jiwon Choi, Nazifa Mouli, Wei Le
Computer Vision · Cross-listed from eess.SP
Multi-View Hierarchical Representation Learning of Fetal Hemodynamics for Maternal Hypertension Detection at the Edge
Alireza Rafiei, Anahí Venzor Strader, Esteban Castro Aragón et al. (+6 more)
Hypertensive disorders of pregnancy remain a leading cause of maternal and fetal morbidity worldwide, yet diagnosis relies on intermittent cuff-based blood pressure measurements that are prone to bias and fail to capture continuous physiological dynamics. Growing evidence suggests that fetal cardiovascular activity is associated with maternal-placental hemodynamics and may encode markers of maternal hypertension. To analyze this, we collected a large-scale
dataset of fetal one-dimensional Doppler ultrasound recordings paired with maternal blood pressure from 3,255 pregnant women across 8,170 antenatal visits in rural Guatemala. We developed AutoHyPE, a hierarchical
attention network that models short- and long-term signal structure, incorporating a novel prototype-based contrastive learning and multi-view strategy to enhance representation robustness under long-tailed class distribution and biological variability. AutoHyPE achieved an AUROC of 0.80 for maternal hypertension detection, outperforming baseline approaches while maintaining balanced performance across classes, with no performance degradation in an edge deployment scenario. Our findings demonstrated that fetal cardiac mechanical activity contains hemodynamic features indicative of maternal hypertension status. This supports a promising paradigm shift toward continuous, objective monitoring of maternal health using existing, low-cost ultrasound technology and introduces a complementary approach to traditional methods based on blood pressure measurements, advancing scalable prenatal care.
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All authors Alireza Rafiei, Anahí Venzor Strader, Esteban Castro Aragón, Victoriana Rosibely Sut Serech, Enma Carolina Coyote Ixen, Reza Sameni, Peter Rohloff, Gari D. Clifford, Nasim Katebi
Computer Vision · Cross-listed from eess.SP
NAKUL-Med: Spectral-Graph State Space Models with Dynamics Kernels for Medical Signals
Badri N. Patro and Vijay S. Agneeswaran
State space models (SSMs) achieve linear-time complexity but struggle with multi-channel physiological signals due to three limitations: fixed kernels cannot capture multi-scale temporal dynamics (motor preparation over hundreds of milliseconds vs. execution transients in tens of milliseconds), Markovian state updates restrict global context for periodic oscillations, and channel-independent processing ignores spatial electrode
topology. We introduce NAKUL, extending SSMs for medical signal analysis through three contributions: (1) Dynamic Kernel Generation-parallel SSM branches with varying kernel sizes (3, 5, 7, 11 timesteps) are weighted by a meta-network that analyzes input statistics, enabling adaptive temporal scale selection; (2) Spectral Context Modeling-FFT-based operations with learnable Gaussian frequency band filters capture global periodic patterns in $O(N \log N)$ complexity; (3) Graph-Guided Spatial
Attention-fixed electrode
topology provides spatial biases to multi-head
attention for principled cross-channel interaction. On BCI Competition IV-2a motor imagery (our primary
benchmark), NAKUL achieves 91.7$\pm$0.6% accuracy, matching
EEG-Conformer (92.1$\pm$0.7%) while using 28% fewer parameters (2.5M vs 3.5M) and 2.0$\times$ faster inference (4.3ms vs 8.7ms). The model generalizes to
EEG emotion recognition (83.6%),
multimodal EEG-fMRI (91.4%), and medical imaging (92.8% on ultrasound), demonstrating architectural versatility. Ablations show dynamic kernels contribute +2.6% and exhibit interpretable scale selection patterns correlated with known neural dynamics.
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Computer Vision
Urban Flood Observations: A hand-labeled training and validation dataset of post-flood inundation
Rohit Mukherjee, Hannah K. Friedrich, Beth Tellman et al. (+5 more)
Urban flooding affects lives and infrastructure worldwide. Mapping inundation in complex urban environments from satellite imagery remains challenging due to limited spatial resolution, infrequent acquisitions, and cloud cover. We present Urban Flood Observations (UFO), a global, hand-labeled
dataset of post-flood inundation in diverse urban settings. UFO comprises 215 image chips (1024 by 1024 pixels) from 14 flood events between 2017 and 2021, derived from 3 m PlanetScope imagery. Each chip is annotated with two classes: 'inundated' (all visible surface water, including floodwater and pre-existing water bodies (permanent or seasonal)) and 'non-inundated'. To demonstrate the
dataset's utility, we trained a
segmentation model using leave-one-event-out cross-validation, achieving a mean Intersection over Union (IoU) of 77.3. We also used UFO to evaluate two widely used surface water products, the Sentinel-1-based NASA IMPACT model and Google's 10 m Dynamic World water class, which yielded IoUs of 44.1 and 48.1, respectively. UFO is publicly available to support the development and validation of urban inundation mapping methods.
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All authors Rohit Mukherjee, Hannah K. Friedrich, Beth Tellman, Ariful Islam, Zhijie Zhang, Jonathan Giezendanner, Upmanu Lall, Venkataraman Lakshmi
Computer Vision
Understanding Representation Gaps Across Scales in Tropical Tree Species Classification from Drone Imagery
Sulagna Saha, Arthur Ouaknine, Etienne Laliberté et al. (+7 more)
Accurate classification of tropical tree species from unoccupied aerial vehicle (
UAV) imagery remains challenging due to high species diversity and strong visual similarity among species at typical image resolutions (centimeters per pixel). In contrast, models trained on close-up citizen science photographs captured with smartphones achieve strong plant species classification performance. Recent advances in
UAV data acquisition now enable the collection of close-up images that are spatially registered with top-view aerial imagery and approach the level of visual detail found in smartphone photographs, with the trade-off that such high-resolution photos cannot be acquired for many trees. In this work, we evaluate the performance of existing methods using paired top-view and close-up
UAV imagery collected in a species-rich tropical forest. Through fine-tuning experiments, we quantify the performance gap between
vision foundation models and in-domain generalist plant recognition models across both image types (high-resolution close-up versus coarser-resolution top-view imagery). We show that classification performance is consistently higher on close-up images than on top-view aerial imagery, and that this performance gap widens for rare species. Finally, we propose that self-supervised representation
alignment across these two spatial scales offers a promising approach for integrating fine-grained visual information into canopy-level species classification models based on top-view
UAV imagery. Leveraging high-resolution close-up
UAV imagery to enhance canopy-level species classification could substantially improve large-scale monitoring of tropical forest biodiversity.
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All authors Sulagna Saha, Arthur Ouaknine, Etienne Laliberté, Carol Altimas, Evan M. Gora, Adriane Esquivel Muelbert, Ian R. McGregor, Cesar Gutierrez, Vanessa E. Rubio, David Rolnick
Computer Vision
AmaraSpatial-10K: A Spatially and Semantically Aligned 3D Dataset for Spatial Computing and Embodied AI
Mohammad Sadegh Salehi, Alexander J.P. Perkins, Igor Pardo Maurell et al. (+2 more)
Web-scale 3D asset collections are abundant but rarely ready to ingest without cleanup, suffering from arbitrary metric scaling, incorrect pivots, brittle geometry, and incomplete textures, defects that limit their use in
embodied AI, robotics, and spatial computing. We present AmaraSpatial-10K, a
dataset of 10,071 synthetic 3D assets standardised for direct ingestion. Each asset ships as a metric-scaled, deterministically anchored .glb with separated PBR maps, a convex collision hull, a paired reference image, and multi-sentence text metadata. Alongside the
dataset we introduce a reusable evaluation suite for 3D asset banks, a continuous Scale Plausibility Score (SPS), a keyword-based Concept Density metric, anchor-error
auditing, and a cross-modal CLIP coherence protocol, and apply it to AmaraSpatial-10K alongside matched subsets of Objaverse, HSSD, ABO, and GSO. We check the annotations independently of the LLM/VLM pipeline that produced them: measured ABO object heights fall inside our scale intervals 88.7-90.7% of the time, and three non-author raters
auditing a stratified sample of 314 assets judge 95.5% plausibly scaled and 99.7% correctly anchored. AmaraSpatial-10K improves CLIP Recall@5 by 3.4x over Objaverse (0.612 vs. 0.181, median rank 267 -> 3), achieves a 99.1% settling-stability rate under Habitat-Sim in static placement and collision tests, with ~20x lower per-load wall time, and as a drop-in Holodeck asset bank improves planned-scale matching and is preferred by blinded human raters in 27 of 40 paired scenes. Controlled ablations on the same asset bank attribute the
retrieval gain to description richness.
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All authors Mohammad Sadegh Salehi, Alexander J.P. Perkins, Igor Pardo Maurell, Ashkan Dabbagh, Raymond Wong
Computer Vision · Cross-listed from cs.CR
DeepSignature: Digitally Signed, Content-Encoding Watermarks for Robust and Transparent Image Authentication
Mathias Graf, Marco Willi, Melanie Mathys et al. (+4 more)
AI-powered generative models have significantly expanded the possibilities for editing, manipulating, and creating high-quality images. Particularly, images that falsely appear to originate from trusted sources pose a serious threat, undermining public trust in image authenticity. We propose DeepSignature, a novel approach that integrates the guarantees of digital signatures with the capabilities of deep neural networks. Neural networks are used both to generate content-encoding watermarks and to embed them imperceptibly into images while ensuring robust extraction. These watermarks are cryptographically verifiable, enabling source attribution and image integrity validation. DeepSignature is compatible with existing image formats and requires no special handling of signed images. It supports client-side verification, requiring only the signer's public key. Additionally, we introduce a novel latent-space verification approach to detect and localize tampering attempts. We evaluate DeepSignature in terms of imperceptibility, robustness to benign transformations, forgery detection, and its resilience against various attack scenarios. Our results highlight the inherent trade-offs between imperceptibility, robustness, and integrity verification. We demonstrate that DeepSignature reliably identifies significant forgery attempts – achieving near 100% in our experiments. Finally, we emphasize DeepSignature's modularity and tunable parameters, allowing adaptation to application-specific requirements. Code and model weights will be published.
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All authors Mathias Graf, Marco Willi, Melanie Mathys, Michael Aerni, Christian Schwarzer, Martin Melchior, Michael H. Graber
Computer Vision · Cross-listed from cs.LG
On-Device Vision Training, Deployment, and Inference on a Thumb-Sized Microcontroller
Jeremy Ellis
This paper presents a complete, end-to-end on-device
vision machine learning pipeline, comprising data acquisition, two-layer CNN training with Adam optimization, and real-time inference, executing entirely on a microcontroller-class device costing $15-40 USD. Unlike cloud-based workflows that require external infrastructure and conceal the computational pipeline from the practitioner, this system implements every step of the core ML lifecycle in approximately 1,750 lines of readable C++ that compiles in under one minute using the Arduino IDE, with no external ML dependencies. Running on the Seeed Studio ESP32-S3 XIAO ML Kit (8 MB PSRAM), the firmware achieves three-class 64x64 image classification in approximately 9 minutes per training run, with real-time inference at 6.3 FPS. Key contributions include: correct batch-level gradient accumulation; pre-computed resize lookup tables for inference; dual-format weight export for SD-free baked-in deployment; a three-tier weight priority system (SD binary > baked-in header > He-initialization) resolved automatically at boot; a single-constant network reconfiguration interface; and PSRAM-aware
memory management suited to microcontroller constraints. All source code and reference
datasets are released under the MIT License at https://github.com/webmcu-ai/on-device-
vision-ai
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Computer Vision
GenAssets: Generating in-the-wild 3D Assets in Latent Space
Ze Yang, Jingkang Wang, Haowei Zhang et al. (+3 more)
High-quality 3D assets for traffic participants are critical for multi-sensor simulation, which is essential for the safe end-to-end development of autonomy. Building assets from in-the-wild data is key for diversity and realism, but existing neural-rendering based reconstruction methods are slow and generate assets that render well only from viewpoints close to the original observations, limiting their usefulness in simulation. Recent
diffusion-based generative models build complete and diverse assets, but perform poorly on in-the-wild driving scenes, where observed actors are captured under sparse and limited fields of view, and are partially occluded. In this work, we propose a 3D latent
diffusion model that learns on in-the-wild
LiDAR and camera data captured by a sensor platform and generates high-quality 3D assets with complete geometry and appearance. Key to our method is a "reconstruct-then-generate" approach that first leverages occlusion-aware neural rendering trained over multiple scenes to build a high-quality latent space for objects, and then trains a
diffusion model that operates on the latent space. We show our method outperforms existing reconstruction and generation based methods, unlocking diverse and scalable content creation for simulation.
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All authors Ze Yang, Jingkang Wang, Haowei Zhang, Sivabalan Manivasagam, Yun Chen, Raquel Urtasun
Computer Vision
Efficient Image Annotation via Semi-Supervised Object Segmentation with Label Propagation
Vitalii Tutevych, Raphael Memmesheimer, Luca Eichler et al. (+4 more)
Reliable object perception is necessary for general-purpose service
robots. Open-vocabulary detectors struggle to generalize beyond a few classes and fully supervised training of object detectors requires time-intensive annotations. We present a semi-supervised label propagation approach for household object
segmentation. A segment proposer generates class-agnostic masks, and an ensemble of Hopfield networks assigns labels by learning representative
embeddings in complementary foundation model
embedding spaces (CLIP, ViT, Theia). Our approach scales to 50 object classes with limited annotation overhead and can automatically label 60% of the data in a RoboCup@Home setting, where preparation time is severely constrained.
Dataset and code are publicly available at https://github.com/ais-bonn/label_propagation.
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All authors Vitalii Tutevych, Raphael Memmesheimer, Luca Eichler, Dmytro Pavlichenko, Fynn Schilke, Rodja Krudewig, Sven Behnke
Computer Vision
Hard to See, Hard to Label: Generative and Symbolic Acquisition for Subtle Visual Phenomena
Renjith Prasad, Rishabh Sharma, Andrew E. Shao et al. (+8 more)
Subtle visual anomalies such as hairline cracks, sub-millimeter voids, and low-contrast inclusions are structurally atypical yet visually ambiguous, making them both difficult to annotate and easy to overlook during active learning. Standard acquisition heuristics based on discriminative uncertainty or feature diversity often overselect dominant patterns while underexploring sparse yet important regions of the data space. This failure mode is especially severe in industrial defect inspection, where anomalies may be both low-prevalence and difficult to distinguish from surrounding structure. To resolve this, we propose GSAL, an active learning framework for object detection that combines a
diffusion-based difficulty signal with a hierarchical semantic coverage prior. The
diffusion component scores images and proposals using reconstruction discrepancy and denoising variability, prioritizing visually atypical or ambiguous examples. However,
diffusion alone does not prevent acquisition from repeatedly favoring hard samples within dominant semantic modes. The semantic component therefore organizes candidate samples in a three-level concept graph and promotes coverage of underrepresented semantic regions while providing interpretable acquisition rationales. By balancing visual difficulty with semantic coverage, GSAL improves
retrieval of subtle and rare targets that are often missed by uncertainty-only selection. Experiments on a proprietary thin-film defect, Pascal VOC and MS COCO
dataset show consistent gains in label efficiency and rare-class
retrieval over uncertainty-, diversity-, and hybrid-based baselines
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All authors Renjith Prasad, Rishabh Sharma, Andrew E. Shao, Annmary Justine Koomthanam, Shreyas Kulkarni, Suparna Bhattacharya, Martin Foltin, Amit Sheth, David Orozco, Matthew Quinn, Brian Sammuli
Computer Vision
CheXmix: Unified Generative Pretraining for Vision Language Models in Medical Imaging
Ashwin Kumar, Robbie Holland, Corey Barrett et al. (+8 more)
Recent medical
multimodal foundation models are built as
multimodal LLMs (MLLMs) by connecting a CLIP-pretrained
vision encoder to an LLM using LLaVA-style finetuning. This two-stage, decoupled approach introduces a projection layer that can distort visual features. This is especially concerning in medical imaging where subtle cues are essential for accurate diagnoses. In contrast, early-fusion generative approaches such as Chameleon eliminate the projection bottleneck by processing image and text
tokens within a single unified sequence, enabling joint representation learning that leverages the inductive priors of
language models. We present CheXmix, a unified early-fusion generative model trained on a large corpus of chest X-rays paired with radiology reports. We expand on Chameleon's autoregressive framework by introducing a two-stage
multimodal generative pretraining strategy that combines the representational strengths of masked autoencoders with MLLMs. The resulting models are highly flexible, supporting both discriminative and generative tasks at both coarse and fine-grained scales. Our approach outperforms well-established generative models across all masking ratios by 6.0% and surpasses CheXagent by 8.6% on AUROC at high image masking ratios on the CheXpert classification task. We further inpaint images over 51.0% better than text-only generative models and outperform CheXagent by 45% on the GREEN metric for radiology report generation. These results demonstrate that CheXmix captures fine-grained information across a broad spectrum of chest X-ray tasks. Our code is at: https://github.com/StanfordMIMI/CheXmix.
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All authors Ashwin Kumar, Robbie Holland, Corey Barrett, Jangwon Kim, Maya Varma, Zhihong Chen, Yunhe Gao, Greg Zaharchuk, Tara Taghavi, Krishnaram Kenthapadi, Akshay Chaudhari
Computer Vision
BrickNet: Graph-Backed Generative Brick Assembly
Peter Kulits and Cordelia Schmid
We train a
language model to generate LEGO-brick build sequences. While prior work has been restricted to discrete, voxel-like towers, we consider a much broader set of pieces, encompassing thousands of part types with diverse connection semantics. To enable this, we first collect a large-scale
dataset of over 100,000 human-designed LDraw brick objects and scenes. The complexity of our setting makes it challenging to autoregressively assemble structures that satisfy physical constraints. When predicting block pose directly, build sequences quickly become invalid after a small number of steps. Although pieces are placed in 3D space, it is the spatial relationships of the parts which define the whole. With this in mind, we design a graph-based program representation that parametrizes structure through connectivity, improving the physical grounding of generated sequences. To enable future applications, we make our
dataset and models available for research purposes. https://kulits.github.io/BrickNet
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Computer Vision
AnemiaVision: Non-Invasive Anemia Detection via Smartphone Imagery Using EfficientNet-B3 with TrivialAugmentWide, Mixup Augmentation, and Persistent Patient History Management
Rahul Patel
Anemia affects over one billion people globally and remains severely under-diagnosed in low-resource regions where laboratory blood tests are inaccessible. This paper presents AnemiaVision, an end-to-end web-based system for non-invasive anemia screening from smartphone photographs of the palpebral conjunctiva and fingernail beds. The proposed pipeline fine-tunes a pre-trained EfficientNet-B3 backbone with a redesigned three-layer classifier head incorporating BatchNorm, GELU activations, and high-rate Dropout (0.45/0.35). Training employs four orthogonal accuracy-boosting techniques: TrivialAugmentWide for policy-free image augmentation, RandomErasing for spatial regularisation, Mixup (alpha=0.2) for inter-class smoothing, and cosine-annealing scheduling with linear warmup. Early stopping is governed by peak validation accuracy rather than validation loss to prevent premature termination on high-variance epochs. The deployed Flask application integrates persistent patient-history management backed by PostgreSQL on Render, with an automated database-migration entrypoint ensuring zero data loss across redeploys. Ablation experiments demonstrate that accuracy-first early stopping contributes +1.6% and Mixup contributes +2.8% to final validation accuracy. Overall, the proposed system achieves a validation accuracy of 96.2% and AUC-ROC of 0.98, compared with 44.9% validation accuracy and AUC-ROC of 0.58 from the three-epoch CPU-only baseline. Sensitivity for the anemic class reaches 0.96, making the system suitable as a first-line screening tool for community health workers in rural settings. The system is publicly accessible and source code is openly available.
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Computer Vision
VS-DDPM: Efficient Low-Cost Diffusion Model for Medical Modality Translation
Nikoo Moradi, Gijs Luijten, Behrus Hinrichs-Puladi et al. (+4 more)
Diffusion models produce high-quality synthetic data but suffer from slow inference. We propose 3D Variable-Step Denoising
Diffusion Probabilistic Model (VS-DDPM) a framework engineered to maintain generative quality while accelerating inference by several factors. We tested our approach on four tasks (missing MRI, tumor removal, MRI-to-sCT, and CBCT-to-sCT) within the BraTS2025 and SynthRAD2025 challenges. Designed for high efficiency under hardware and time constrains imposed by both challenges. VS-DDPM achieved state-of-the-art (SOTA) performance in missing MRI synthesis, yielding Dice scores of 0.80, 0.83, and 0.88 for the enhancing tumor, tumor core, and whole tumor regions, respectively, alongside a structural similarity index (SSIM) of 0.95. For MRI tumor removal, the model attained a root mean squared error (RMSE) of 0.053, a peak signal-to-noise ratio (PSNR) of 26.77, and an SSIM of 0.918. While the framework demonstrated competitive performance in MRI-to-sCT and CBCT-to-sCT tasks, it did not reach SOTA
benchmarks, potentially due to sensitivities in data pre and post-processing pipelines or specific loss function configurations. These results demonstrate that VS-DDPM provides a robust and tunable solution for high-fidelity 3D medical image synthesis. The code is available in https://github.com/andre-fs-ferreira/SynthRAD_by_Faking_it.
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All authors Nikoo Moradi, Gijs Luijten, Behrus Hinrichs-Puladi, Jens Kleesiek, Victor Alves, Jan Egger, André Ferreira
Computer Vision · Cross-listed from cs.CL
Self Knowledge Re-expression: A Fully Local Method for Adapting LLMs to Tasks Using Intrinsic Knowledge
Mengyu Wang, Xiaoying Zhi, Zhiyi Li et al. (+4 more)
While the next-
token prediction (NTP) paradigm enables large
language models (LLMs) to express their intrinsic knowledge, its sequential nature constrains performance on specialized, non-generative tasks. We attribute this performance bottleneck to the LLMs' knowledge expression mechanism, rather than to deficiencies in knowledge acquisition. To address this, we propose Self-Knowledge Re-expression (SKR), a novel, task-agnostic adaptation method. SKR transforms the LLM's output from generic
token generation to highly efficient, task-specific expression. SKR is a fully local method that uses only unannotated data, requiring neither human supervision nor model
distillation. Experiments on a large financial document
dataset demonstrate substantial improvements: over 40% in Recall@1 for information
retrieval tasks, over 76% reduction in object detection latency, and over 33% increase in anomaly detection AUPRC. Our results on the MMDocRAG
dataset surpass those of leading
retrieval models by at least 12.6%.
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All authors Mengyu Wang, Xiaoying Zhi, Zhiyi Li, Robin Schmucker, Shay B. Cohen, Tiejun Ma, Fran Silavong
Computer Vision · Cross-listed from eess.IV
CT-Guided Spatially-varying Regularization for Voxel-Wise Deformable Whole-Body PET Registration
Xiangcen Wu, Ruohua Chen, Sichun Li et al. (+4 more)
Whole-body Positron Emission
Tomography (PET) registration is essential for multi-parametric tumor characterization and assessment of metastatic disease progression. In deep learning-based deformable registration, the dense displacement field (DDF) regularizer is crucial for stabilizing optimization and preventing unrealistic deformations in large 3D volumes. A key challenge in whole-body deformable registration is anatomical heterogeneity, rigid structures (e.g., bones) should undergo stronger regularization, whereas soft tissues require more flexible deformation and weaker constraints. In this work, we propose a simple yet effective CT-guided spatially-varying regularization strategy for whole-body cross-tracer deformable PET registration. The key idea is to use the paired CT volume from the PET/CT acquisition to construct a voxel-wise regularization map for the DDF, replacing the conventional single global regularization weight. This yields anatomy-adaptive regularization strength across rigid and soft tissues. The proposed method is evaluated on a real clinical cross-tracer PET/CT
dataset of 296 patients involving 18F-PSMA and 18F-FDG, showing that the proposed method achieves statistically significant improvements over weakly-supervised registration baseline in both whole-body registration performance and organ-wise
alignment.
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All authors Xiangcen Wu, Ruohua Chen, Sichun Li, Qianye Yang, Sheng Liu, Jianjun Liu, Zhaoheng Xie
Computer Vision · Cross-listed from eess.IV
Triple-Phase Sequential Fusion Network for Hepatobiliary Phase Liver MRI Synthesis
Qiuli Wang, Xinhuan Sun, Fengxi Chen et al. (+7 more)
Gadoxetate disodium-enhanced MRI is essential for the detection and characterization of hepatocellular carcinoma. However, acquisition of the hepatobiliary phase (HBP) requires a prolonged post-contrast delay, which reduces workflow efficiency and increases the risk of motion artifacts. In this study, we propose a Triple-Phase Sequential Fusion Network (TriPF-Net) to synthesize HBP images by leveraging the sequential information from pre-HBP sequences: while T1-weighted imaging serves as the indispensable baseline, the model adaptively integrates arterial-phase (AP) and venous-phase (VP) features when available. By modeling the tissue-specific contrast uptake and excretion dynamics across these three phases, TriPF-Net ensures robust HBP synthesis even under the
stochastic absence of one or both dynamic contrast-enhanced sequences. The framework comprises an Enhanced Region-Guided Encoder and a Dynamic Feature Unification Module, optimized with a Region-Guided Sequential Fusion Loss to maintain physiological consistency. In addition, clinical variables, including age, sex, total bilirubin, and albumin, are incorporated to enhance physiological consistency. Compared with conventional methods, TriPF-Net achieved superior performance on
datasets from two centers. On the internal
dataset, the model achieved an MAE of 10.65, a PSNR of 23.27, and an SSIM of 0.76. On the external validation
dataset, the corresponding values were 12.41, 23.11, and 0.78, respectively. This flexible solution enhances clinical workflow and lesion depiction, potentially eliminating the need for delayed HBP acquisition in HCC imaging.
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All authors Qiuli Wang, Xinhuan Sun, Fengxi Chen, Yongxu Liu, Jie Cheng, Lin Chen, Jiafei Chen, Yue Zhang, Xiaoming Li, Wei Chen
Computer Vision
On the Complementarity of Quantum and Classical Features: Adaptive Hybrid Quantum-Classical Feature Fusion for Breast Cancer Classification
Yasmin Rodrigues Sobrinho, João Renato Ribeiro Manesco and João Paulo Papa
The integration of
quantum machine learning with classical deep learning offers promising avenues for medical image analysis by mapping data into high-dimensional
Hilbert spaces. However, unifying these paradigms remains challenging due to optimization asymmetries. We propose a hybrid
quantum-classical architecture for breast cancer diagnosis based on a dual-branch feature-extraction pipeline. Our framework unifies complementary representations from classical models and trainable or deterministic (non-trainable)
quantum circuits. Three fusion strategies are introduced: Static Hybrid Fusion (SHF) for offline extraction, Dynamic Hybrid Fusion (DHF) for end-to-end co-adaptation, and Temperature-Scaled Hybrid Fusion (TSHF). Inspired by
multimodal learning, TSHF uses a learnable scalar to balance branch gradient dynamics and address optimization bottlenecks. We evaluate BreastMNIST, INbreast, and BUS-UCLM, spanning ultrasound and mammography, using ResNet-18 and a shallow CNN, with five independent runs per configuration. Fusion improves over the strongest classical baseline on all three
benchmarks. On BreastMNIST, TSHF with ResNet-18 and a non-trainable
circuit achieves 88.33% accuracy, 92.09% F1-score, and 92.09% AUC-ROC, versus 84.74% accuracy and 87.08% AUC-ROC for ResNet-18 alone. On INbreast, SHF with the same pairing performs best, at 70.42% accuracy, 72.96% F1-score, and 80.28% AUC-ROC. On BUS-UCLM, SHF with a trainable
circuit achieves 78.46% accuracy and 84.66% F1-score, over seven accuracy points above the best standalone branch. Adaptive fusion is not universally beneficial: static fusion performs best on the two smaller
datasets, suggesting an additional estimation burden from co-adaptation and learned calibration under limited data. Clinical applicability requires validation beyond the small, low-resolution
datasets and simulated
quantum circuits considered here.
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