Papers

In seismology and related fields, the measurement of rotation in all three spatial dimensions is essential to complement the observation of translations. Access to all six degrees of freedom allows for full reconstruction of seismic wavefields and improves the understanding of complex ground motion during seismic events. In this regard, Sagnac interferometers in the form of large active ring laser systems have demonstrated remarkable performance. So-called passive ring gyroscopes offer the potential to bypass some of the limitations of active ring lasers and could represent a promising complement to existing sensor technology. Here, we present a prototype of a transportable three dimensional free-space passive ring gyroscope, reaching a sensitivity in the micro rad/s/sqrt(Hz) regime in all spatial dimensions. We demonstrate the sensor performance by reconstructing the rotational components of a simulated seismic event.

We propose a scheme for realizing thermal logic gates at the nanoscale using a phononic ring system. Two atomic sites, placed in close proximity to the ring, serve as the inputs for two-input logic operations, while a single proximity site is employed for single-input logic functionality. The logic output is encoded in the phonon transmission probability, which is calculated within the framework of non-equilibrium Green's function formalism. By appropriately tuning the ring-electrode junction configuration, all seven standard logic gates, comprising three fundamental and four combinatorial operations, are successfully realized in different phonon frequency regimes. Our results suggest that the proposed logic operations remain valid over a broad range of phonon frequencies, highlighting the generality and reliability of the proposed approach.

Valley polarization in 2D TMDs is promising for low-power valleytronic and spin-valley information processing, but time-reversal symmetry in pristine nonmagnetic TMDs keeps the K+ and K- valleys degenerate, limiting device applications. In this work, we investigated the structural stability, electronic properties, and tunable valley polarization of V-alloyed MoTe2 monolayer, Mo0.75V0.25Te2, using first-principles density functional theory (DFT) calculations. Substitutional alloying of MoTe2 with V introduced magnetic exchange interaction, which, together with spin-orbit coupling (SOC), lifted the valley degeneracy at the unequal valleys. The alloyed structure was found to be energetically and dynamically stable due to the absence of imaginary phonon modes. In pristine MoTe2, SOC produced spin splittings of 34.0 meV and 218.9 meV in the conduction bands and valence bands, respectively, but no valley polarization was observed. In contrast, Mo0.75V0.25Te2 exhibited spontaneous valley polarization of 37.3 meV in the conduction band and 78.2 meV in the valence band. The valley polarization was further enhanced by external electric fields and biaxial strain. A transverse electric field along the crystal c axis produced the maximum valley splitting of 132.8 meV in the valence band, whereas biaxial tensile strain increased the valence band valley splitting up to 160.8 meV. The maximum conduction band valley splitting reached 54.4 meV under 2% biaxial compressive strain. These results demonstrated that V alloying, combined with electric-field and strain engineering, provides an effective strategy for achieving large and tunable valley polarization in MoTe2. Thus, Mo0.75V0.25Te2 can be considered a promising 2D platform for tunable valleytronic device applications, such as transistors and sensors.

Hyperspectral infrared observations are an important data source for numerical weather prediction (NWP) because they provide rich information on the vertical structure of atmospheric temperature and humidity. However, most existing deep learning methods mainly focus on one-way retrieval from radiances to atmospheric profiles, while the reverse radiance simulation process and the consistency between atmospheric state space and radiance observation space are insufficiently considered. In this study, we propose SIMBA, a unified bidirectional retrieval-forward simulation framework for FY-4A GIIRS hyperspectral infrared radiance modeling toward NWP applications. The framework jointly performs atmospheric profile retrieval and radiance reconstruction, introduces a cycle-consistency constraint to strengthen the coupling between the two processes, and employs a bidirectional Mamba state-space module to capture long-range dependencies along pressure levels. Using collocated FY-4A GIIRS observations and ERA5 reanalysis data, the proposed method is evaluated for temperature retrieval, specific humidity retrieval, long-wave radiance reconstruction, and medium-wave radiance reconstruction. Experimental results show that SIMBA outperforms several representative deep learning baselines across both retrieval and reconstruction tasks, while ablation experiments confirm the contribution of the bidirectional design and cycle-consistency mechanism. These results demonstrate that the proposed framework is effective for joint atmospheric profile retrieval and hyperspectral infrared radiance modeling, and suggest potential for future Jacobian-related analysis and NWP-oriented extensions.

Phosphatidylcholine liposomes fill a special niche in alleviating osteoarthritis via intra-articular (IA) administration, attributed to their superlubricity at the articular cartilage surface, but their co-utilization as drug delivery vesicles in such therapy remains challenging as they may rupture under mechanical stress. Here, we describe cytoskeleton-inspired, supramolecular, self-assembled nanolipogels (NLGs), encompassing liposome-encased nanogels with a dynamic network formed by hydrogen bonding and cation-pi interactions, as a platform for simultaneous robust drug-delivery and massive reduction of interfacial frictional dissipation. We use a surface force balance to assess such dissipation at the sub-nanometer level, elucidating the mechanism involved, and atomic force microscopy to probe the NLGs structural stability. A useful proxy for the interfacial dissipation is the coefficient of friction, which remains as low as 10-4 at contact pressures at least up to 2 MPa, while under higher pressures exceeding the H-bonding energy density it increases abruptly and irreversibly to the still-low value 10-2. Under sustained sliding above this threshold, however, friction gradually decreases again, indicating recovery of the lubricating interface. Molecular dynamics simulations identify the compressive stress decrease due to hydrogen-bond rupture/rearrangement within the nanogel as a buried supramolecular transition associated with lubrication breakdown and recovery, while cargo release during sliding emphasizes the drug-delivery potential of such NLGs. These findings reveal how supramolecular core-shell reinforcement regulates load-bearing hydration lubrication, and provides a framework for designing adaptive biomimetic lubricants which are at the same time load-bearing intra-articular cargo-delivery vehicles.

Viscous fingering instabilities during fluid displacement in porous media can compromise the efficiency of applications such as enhanced oil recovery, CO2 sequestration, and groundwater remediation. While extensive research exists on linear stability analysis for fully immiscible and fully miscible displacements, the intermediate case of partially miscible flow with limited mass transfer between phases remains largely unexplored. This study extends linear stability analysis to a two-phase, two-component system that accounts for gravity effects, fractional flow, capillary forces, mechanical dispersion, and interphase mass transfer, focusing on the case where a partially miscible gaseous fluid displaces a liquid. We formulate an eigenvalue problem to characterize instability growth rates and cutoff wavenumbers. The resulting ordinary differential equations have discontinuous coefficients at the transition from two-phase to pure-liquid flow, resulting in discontinuous eigenfunction derivatives. We derive jump conditions for the derivatives at this transition, and solve the eigenvalue problem using the matched initial value problem method. Results demonstrate that mass transfer has a pre-dominantly stabilizing effect by reducing viscosity contrast and altering shock properties at the displacement front. This stabilizing influence is particularly pronounced for high viscosity contrasts and dampens gravity-induced instability in upward displacements. Mass transfer most significantly affects the perturbation growth rate, while its effect on the cutoff wavenumber is less pronounced. We identify a critical value for the dimensionless longitudinal dispersion coefficient where both growth rate and cutoff wavenumber are maximized, suggesting complex interactions between capillary forces and mechanical dispersion.

Recent experiments combining electrophoresis with pressure-driven flows in microchannels have revealed that microparticles undergo lateral migration perpendicular to the applied electric field. Although fluid inertia has been proposed as a possible explanation, inertial effects are negligibly small in these regimes, leaving the underlying physical mechanism an open question. In this study, we address these observations by extending previous theoretical work on concentration polarization,i.e., the external-field-induced modification of the ionic concentration field surrounding a dielectric object. We consider a dielectric particle with surface conductance subjected simultaneously to an external electric field and a shear flow. We show that the shear flow breaks the symmetry of the ionic concentration around the particle in the direction perpendicular to the applied field, thereby driving lateral migration. We demonstrate that the resulting migration velocity comprises two distinct contributions: an electrophoretic and a diffusiophoretic component. Our theory yields an explicit expression for the velocity magnitude as a function of the zeta potential and the Dukhin number, predicting typical speeds on the order of $\mathrm{\mu}$m/s for representative experimental parameters. Notably, the model also predicts a reversal in the migration direction for Dukhin numbers of order unity.

We develop a structure-oriented randomized neural network framework, termed SO-RaNN, for the Poisson-Nernst-Planck (PNP) system and the Poisson-Nernst-Planck-Navier-Stokes (PNP-NS) system. The decoupled linearized subproblems are solved iteratively by randomized neural networks in a space-time framework. For the concentration variables, a pointwise cut-off is used to enforce positivity at the value level, and discrete mass-scaling factors are computed at selected correction instants and interpolated in time, so as to ensure exact mass matching at those instants and to promote approximate mass preservation between them. To introduce an auxiliary discrete dissipation mechanism, we further employ an SAV-type post-processing correction, which yields monotonicity of the SAV auxiliary variable under the ideal SAV update. For the PNP-NS system, a structure-preserving randomized neural network (SP-RaNN) is used for the velocity field, so that the velocity approximation satisfies the incompressibility constraint pointwise by construction. On the theoretical side, we derive residual-based estimates for the raw, uncorrected RaNN solvers of the linearized subproblems, formulate a conditional local-in-time convergence result for the raw outer Picard iteration of the PNP system, and analyze the value-level positivity correction together with the mass-correction and SAV post-processing steps. For the PNP-NS system, we establish an approximation result for the SP-RaNN space and provide a conditional error statement for the corresponding linearized Oseen-type problem. Numerical experiments demonstrate approximation accuracy in the source-driven manufactured tests and illustrate the intended value-level positivity correction, selected-time mass matching, computed free-energy curves based on the final gauge-fixed potential, and divergence-free approximation in benchmark tests.

The question of optimal experimental design has been addressed in a vast variety of contexts and answered using manifold approaches. Assuming additive white Gaussian noise, this work applies the Bayesian framework for design optimization to the posterior distribution after marginalization over linear parameters and discusses the implications. Examples of exponentially decaying signals with and without oscillations complement the discussion. Application of the examples considered include but are not limited to nuclear magnetic resonance and relaxometry experiments using solid-state spins sensors.

Velocity slip at the solid–fluid (SF) interface plays a key role in fluid transport at the nanoscale, and the SF friction coefficient has been extensively studied because it indicates the degree of slippage. Owing to the scale of this phenomenon, molecular dynamics (MD) simulations are commonly employed using two major approaches: the Green-Kubo integral method in equilibrium MD (EMD), and the direct calculation of friction force and slip velocity in non-equilibrium MD (NEMD) systems under shear. Regarding the latter, a strict definition of the slip velocity is missing due to the nonzero thickness of the boundary at the microscale, and the average velocity of the first adsorption layer or the velocity at the boundary obtained by extrapolation or interpolation is often used. In this study, we propose an alternative description of the slip velocity based on a thermal perspective from the two different scales, i.e., at the macroscale, frictional heat is defined as the product of the friction force and slip velocity, whereas at the microscale, it can be expressed as the sum of the works exerted on the fluid and solid by each other. By combining the two different scales, we defined the slip velocity based on the dissipation induced at the SF interface under shear, which avoids the arbitrariness in the slip velocity at the microscale.

Haematocrit influences blood viscosity and may affect coronary computational fluid dynamics (CFD). However, previous studies examined broad or pathological haematocrit ranges, and it remains unclear whether female-specific haematocrit variations within the physiological range produce meaningful changes in coronary haemodynamics. 15 female coronaries were analysed, including healthy arteries and diseased models with mild, moderate and severe stenosis. A haematocrit-dependent Carreau-Yasuda model was developed. CFD simulations were performed using the standard rheology model and a female-specific haematocrit-based model (40%). Time-averaged endothelial shear stress (TAESS), ESS gradient (ESSG), temporal shear variation index (TSVI), helicity, and low/high TAESS exposure were compared across coronary trees, arterial segments, bifurcations, stenosed vessels and corresponding narrowed regions. The female-specific model produced statistically significant differences from the standard model across all metrics and coronary regions (p < 0.05). However, the absolute differences were small, indicating a limited haemodynamic impact. Bland-Altman analysis showed narrow biases and limits of agreement. Linear regression demonstrated significant associations between inter-model differences and haemodynamic magnitude for TAESS, ESSG, helicity intensity, and adverse TAESS exposure, but the slopes were small. Similar findings were observed in stenosed arteries, where both models captured comparable flow disturbances across stenosis severities. Female-specific haematocrit variation within the physiological range is computationally detectable but haemodynamically negligible in coronary CFD. A standard rheology model is therefore likely sufficient for most coronary CFD studies, while personalised haematocrit modelling is more relevant for patients with abnormal haematocrit or rheology-focused studies.

This work follows the evolution of financial networks in Norway over a period of nine years at a monthly rate. The data consist of board directors and their affiliations to companies, which we model as simplicial complexes. In this framework, directors are represented as nodes and companies as faces of the complex. To characterize the latter, we focus on three topological measures: the Euler characteristic, computed through the Betti numbers, torsion computed through the reduced determinant of the higher-order Laplacians, and higher-order clustering coefficients. The first two fail to capture the effect of imposed law on representation, unlike our notion of curvature which is a geometrical measure computed from the coefficients of the series expansion of the heat kernel in powers of time, which is our major contribution in this work. In particular, the Euler characteristic integrates curvature, and thus local information is lost. Subsequently, not every topological measure can reliably capture shocks in networks. Further, the number of spanning trees may undergo significant changes at the lowest order, yet these changes need not be reflected in the torsion. Conversely, the change in the curvature revealed variation in the board interlock due to legislation, and serves as a sensitive measure for detecting shocks in networks. Inflection points in curvature are associated with external forcing, and minima with shock arrival times. Sharp transitions are also observed in the components of torsion, while smooth changes are observed in higher-order clustering.

We introduce SEA-PINN, a novel architecture that incorporates a Squeeze-Excitation-like attention mechanism into physics-informed neural networks to dynamically recalibrate the importance of neurons across layers. A key feature of SEA-PINN is its highly stable initialization. On 17 out of 20 benchmark problems, SEA-PINN exhibit nearly negligible variance and significantly reduced initial loss, establishing a quasi-deterministic and favorable starting point for optimization. Notably, without employing Fourier feature embeddings or periodic activation functions, SEA-PINN attained competitive accuracy (83% vs. 90% improvement relative to FNN-PINN on the high-frequency case 7) as compared with TSA-PINN-a model specifically engineered for high-frequency problems via learnable frequencies in sinusoidal activations. Furthermore, integrating SEA-PINN into TSA-PINN boosted performance by 42.49%. These results underscore SEA-PINN as a lightweight plug-in module that enhances nonlinear representation power, promotes more robust and efficient convergence, and strengthens the overall reliability of physics-informed learning.

We introduce a shape-based polar order parameter that captures the structural asymmetry of cells within epithelial monolayers. By combining bright-field imaging and traction force microscopy, we demonstrate that shape polarity serves as a unifying biomechanical metric, integrating the physical information encoded by nematic directors, principal stresses, and cellular motion. Furthermore, we show that the tissue organizes into a mixed polar-nematic phase, characterized by the coexistence of integer ($\pm 1$) and half-integer ($\pm 1/2$) defects. Through mechanical perturbations, we demonstrate that both substrate stiffness and cell-cell adhesion modulate the density of these excitations and the length of domain walls binding like-signed positive half-integer defects. Using a minimal continuum model of polar-nematic active matter, we establish that this mixed phase is fundamentally driven by the interplay of active stresses and polar-nematic elasticity. These findings provide a direct experimental evidence that epithelial monolayers behave as nematopolar matter, in which coupled polar and nematic elastic interactions jointly shape the active state

Imaging flow cytometry (IFC) enables high-throughput single-cell analysis but largely relies on fluorescence labeling to obtain molecular specificity. Label-free vibrational imaging can provide intrinsic chemical contrast, yet coherent Raman-based methods interrogate only a limited axial volume, which restricts quantitative whole-cell analysis under flow. Mid-infrared photothermal (MIP) microscopy offers a promising route to overcome this limitation by combining linear mid-infrared (MIR) absorption-based chemical contrast with visible-light detection, allowing chemical imaging of a broader axial volume of each cell in a wide-field configuration. However, applying MIP microscopy to rapidly flowing cells has been difficult because conventional frame-sequential acquisition of MIR-ON and MIR-OFF images is highly susceptible to motion-induced subtraction artifacts. Here we demonstrate MIP-IFC, a label-free imaging flow cytometry platform based on single-shot nanosecond-dual-pulse MIP (SNAP-MIP) microscopy. SNAP-MIP encodes the MIR-ON and MIR-OFF states into separate holographic channels within a single camera exposure, reducing their temporal separation to 20 ns. This single-shot acquisition suppresses motion artifacts and increases the allowable sample velocity for artifact-free MIP imaging by five orders of magnitude compared with conventional frame-sequential MIP imaging. Leveraging this capability, MIP-IFC acquired chemical images at 500 frames per second and achieved a cellular event rate up to ~70 events s^-1. We demonstrate quantitative chemical discrimination of flowing microbeads and apply MIP-IFC to single-cell profiling of oleic-acid-induced lipid accumulation, adipocyte differentiation, and confluence-dependent cellular heterogeneity. These results establish MIP-IFC as a high-throughput, quantitative, label-free chemical imaging platform for single-cell phenotyping under flow.

We investigate the seasonal phase locking of the El Niño-Southern Oscillation (ENSO) in a linear stochastic recharge oscillator (SRO), a damped oscillator with additive noise and a time-dependent growth rate. Phase locking is reflected in the seasonality of the variance of the sea surface temperature anomaly (SSTA). In general, energy drives such a change, whereas entropy governs whether it occurs; phase locking is thus subject to both an energy- and an entropy-based constraint. We quantify this entropy-based constraint using a thermodynamic uncertainty relation (TUR), a fundamental inequality in stochastic thermodynamics. The TUR constrains the tendency of the SSTA variance by the partial entropy production rate, which is dominated by the ratio of forward and backward transition probabilities and quantifies the irreversibility of SSTA transitions. The growth rate governs this irreversibility: its extrema occur in boreal autumn and late winter, and the entropy production rate peaks at both times. These peaks relax the TUR constraint on the tendency of the SSTA variance, so that the variance itself can peak in boreal winter, consistent with observed ENSO phase locking. Conversely, when irreversibility is insufficient, ENSO cannot grow or decay. If this irreversibility were interpreted as dissipated energy, the constraint on ENSO growth and decay would require this dissipation to be exported from the equatorial Pacific. A more realistic model is needed to test this hypothesis and to further explore the physical connection between entropy and dissipated energy.

We estimate that data centers caused average retail electricity rates to fall modestly in the United States from 2015 to 2024 using an instrumental variables approach. Despite prevailing sentiment, the finding is consistent with economic reasoning: existing large power system fixed costs, economies of scale in transmission and distribution, and declining unit costs for generation imply that durable demand growth lowers average prices. We find patterns of economies of scale for transmission, distribution, and generation costs as well as within and across retail customer classes. We caution that future supply constraints could reverse the effect.

Diode-pumped solid-state (DPSS) lasers play a central role in modern photonics owing to their exceptional efficiency and ability to extend spectral coverage beyond the reach of semiconductor diodes. These attributes have enabled breakthroughs in precision metrology, quantum optics, and coherent communications. However, bringing the proven advantages of DPSS gain media such as Nd:YAG onto an integrated photonic platform has remained difficult, largely due to inefficient pump utilization and limited power-scaling in chip-scale implementations. Here, we demonstrate the first photonic-integrated Nd:YAG laser-amplifier system that overcomes these challenges with a micro-chip based master-oscillator-power-amplifier (\mu-MOPA) architecture. The seed laser, employing a double-resonant microring resonator, could reach a threshold as low as 2.9 \mu W. The single-pass waveguide amplifier, when optimized separately, provides up to 46.6 dB small-signal gain. Combining the low-threshold seed with cascaded waveguide amplifiers, the integrated \mu-MOPA delivers more than 12 dBm of amplified continuous-wave output power. These results establish Nd:YAG waveguide integration as a practical route to compact and high-performance solid-state light sources.

With 890,000 annual new cases globally, head and neck squamous cell carcinoma has one of the highest recurrence rates among solid malignancies. Although frozen section analysis is the standard of care for intraoperative margin assessment, accurately relocating detected positive margins on the resection bed remains challenging due to imprecise alignment between resected specimens and their resection bed, compounded by post-resection mucosal tissue shrinkage. We present a biomechanics-driven deformable registration framework that corrects post-resection tissue deformation to provide intraoperative guidance. Our approach registers 3D specimen meshes to intraoperative resection bed point clouds using a deformable registration approach based on regularized Kelvinlet basis functions. The registration matches surface point clouds, fiducial landmarks, and boundary contour constraints that directly penalize perpendicular distance-to-agreement between specimen and resection bed boundaries. Across nine specimens from skin, buccal mucosa, and tongue sites, the overall mean target registration error was $11.11 \pm 4.07$ mm using rigid registration, which decreased to $8.20 \pm 2.68$ mm (26.19% reduction) using deformable registration without contour constraint. The proposed contour-constrained deformable registration further reduced the error to $5.62 \pm 2.28$ mm, a 49.41% reduction relative to rigid registration. We observed the largest reduction in the most clinically challenging tongue specimens. We also performed a systematic two-stage parameter search to characterize the relative importance of surface alignment, fiducial correspondences, contour constraint, and strain energy regularization. This search revealed that contour weighting dominates registration accuracy for tissue types with large lateral deformation, while the algorithm operates over a broad range of parameter combinations.

We present a study of charge sharing and electronic cross-talk in second-generation Large-Area Picosecond Photodetectors (LAPPD Gen 2). The LAPPD is a vacuum-based device consisting of a photocathode, two microchannel plates, and a resistive anode that capacitively couples to an 8 $\times$ 8 pixelated readout board (25.4 mm $\times$ 25.4 mm pixel area). Using a picosecond pulsed laser, we measure signal distributions across the resistive anode and quantify coupling between target and neighboring pixels. We further examine the relationship between dark-count rate and LAPPD voltage settings, identifying decay behavior characterized by fast, intermediate, and slow relaxation timescales. We additionally observe the LAPPD behaving as a resonant cavity by injecting electrical pulses into the readout board. To further interpret observed signals, we develop a pulse-classification method and identify additional features at approximately 60 ns and 110 ns. Finally, we implement a first-principles Monte Carlo simulation to model the radial and temporal distributions of observed signals, including contributions from electron backscatter and potential ion afterpulsing. The simulation shows reasonable agreement with the experimentally derived pulse classifications.

Strong light-matter and electron-phonon coupling generate ground states dressed by virtual bosonic excitations, making bare-state truncations and perturbative treatments unreliable in the ultrastrong-coupling regime. We introduce a nonperturbative variational ground-state framework based on a state-dependent polaron transformation, combined with a product-state ansatz and a second-order perturbative correction for residual matter-boson entanglement. We show that the optimized transformed frame becomes asymptotically decoupled at infinite coupling, because the leading linear coupling is canceled while off-diagonal matter transitions are suppressed by displaced-oscillator overlaps. The approach is asymptotically correct in both weak- and strong-coupling limits and remains accurate in the intermediate regime, where fixed polaron transformations are least reliable. Dicke-model benchmarks reproduce ground-state energies, fidelities, and the superradiant transition, with second-order energy errors below 0.2%. Holstein-model benchmarks yield errors below 0.5% and clarify how translational symmetry affects wave-function quality. This dressed-basis framework enables nonperturbative modeling of strongly coupled light-matter and electron-phonon systems.

We present a forcing-informed (FI) resolvent analysis framework to identify input-output relations for statistically stationary self-sustained unsteady flows. The central idea of this method is to inform the resolvent operator about the spatiotemporal structures of the nonlinear terms that act as exogenous forcing with respect to the mean flow. To construct the FI resolvent operator, we estimate the basis vectors for the input subspace spanned by forcing snapshots and, similarly, for the output subspace, from simulation data. The extracted FI response and forcing modes are expressed through the estimated bases of the output and input subspaces, respectively, and the singular values of the FI resolvent operator correspond to the actual output amplitudes. These properties ensure that the extracted modes are consistent with the actual self-sustained flow fields. Additionally, the forcing snapshots can be used to construct the linear operator, enabling a fully data-driven FI resolvent analysis. The proposed framework is validated using the Stuart-Landau oscillator and demonstrated for a two-dimensional cylinder wake and a three-dimensional transitional boundary layer. We successfully identify the gains and the corresponding pairs of forcing and response modes, even at frequencies where the nonlinear amplification mechanism is crucial. Furthermore, leveraging the balance between the time-averaged energy amplification/attenuation by the linear operator and nonlinear forcing, we introduce a nonlinear energy transfer map that identifies the spatial domains where the extracted forcing mode injects or removes fluctuation energy, thereby providing key physical insight into the self-sustaining mechanisms.

Optical forces in focused-beam traps are generally nonconservative, yet the controlled use of this nonconservative component for airborne single-particle dynamics remains limited. We demonstrate a dual-beam optical trap in which a single aerosol can be switched between localized confinement and sustained orbital motion by tuning the relative positions of two counter-propagating foci. The axial separation controls the onset of nonconservative circulation, while the lateral offset tunes the projected orbit size and causes a monotonic change in the rotation frequency. T-matrix optical force calculations and Langevin simulations support this interpretation by showing that finite axial misalignment activates a circulating force component, whereas near-zero axial separation gives a confinement-dominated force field. Experiments confirm the predicted switching behavior through mean-square displacement and frequency measurements. We further show that the projected orbit geometry provides a particle-dependent observable, with the orbit anisotropy Ay/Ax varying systematically with aerosol diameter. The results provide a compact, low-power platform for controlled orbital dynamics of single airborne particles and for future aerosol measurements based on nonequilibrium trajectory observables.

As silicon photonic integrated circuits (PICs) scale in complexity, testing and calibration increasingly depend on effective phase modulation mechanisms. This work compares thermally induced phase modulation and carrier-based electrical modulation in Mach-Zehnder and microring modulators. The devices are designed and evaluated for extinction ratio, tuning efficiency, power consumption, and modulation bandwidth. The study identifies key trade-offs among modulation speed, energy consumption, and tuning controllability that directly influence the suitability of these methods for test signal generation and calibration tasks. The results highlight the relative advantages and limitations of thermal and electrical approaches across different operating regimes. These findings provide practical design guidance for selecting phase modulation strategies in scalable silicon photonic systems with integrated test and calibration requirements.

Laminar-to-turbulent transition delay is a key challenge in hypersonic boundary-layer flows. Unstable disturbances-most prominently the first and second modes-trigger the onset of turbulence and pose a fundamental technological barrier to hypersonic transport. While existing control strategies target the second mode, simultaneous mitigation of the first mode has long appeared physically impossible. A new flow-control concept is introduced in which phase relations between wall pressure and velocity fluctuations are tailored using subsurface phonon engineering to control both modes concurrently. The outcome is substantial drag reduction and alleviation of the extreme thermal loads associated with turbulence.

Extending earlier work in Physics-informed Meta-instrument for eXperiments (PiMiX) [1], PiMiX~2.0 is an artificial-intelligence (AI)-enhanced data-fusion and analysis framework that integrates multi-experiment multi-modal radiographic imaging and tomography (RadIT) with physics-informed reasoning and agentic AI workflows. The framework supports automated data ingestion, multimodal image processing from one or more experiments, three-dimensional (3D) and time-resolved three-dimensional (4D) reconstruction, and physics-aware interpretation of experimental observations. The PiMiX agents are designed for deployment on desktop and laptop systems commonly used in experimental workflows, while remaining scalable to high-performance computing environments for computationally intensive tasks. By coupling RadIT instrumentation and measurements with geometry, physics, computation, and statistical inference, PiMiX 2.0 aims to accelerate RadIT data processing, knowledge extraction, improve reproducibility, and enable more integrated analysis and workflows in high-temperature plasmas, nuclear fusion, advanced manufacturing, other static and dynamic experiments.

We reconstruct unitary quantum dynamics from a minimal axiomatic foundation built on Hilbert-space observables and isospectral evolution. The only dynamical assumption is that physical time evolution is a continuous one-parameter flow of Hermitian observables that preserves their spectra, i.e. the possible outcomes of measurement. We show that this assumption is already sufficient to force the Lax form of quantum dynamics. The Heisenberg equation, the time-dependent and time-independent Schrödinger equations, conservation laws, and good quantum numbers then follow as theorems rather than postulates. In this formulation, Lax pair theory supplies the missing dynamical bridge between the measurement structure of a Hilbert space and standard quantum evolution: the Hamiltonian is not assumed, but emerges as the generator required for an isospectral observable flow.

Invasive mechanical ventilation is a lifesaving therapy, but timely, safe discontinuation is essential to preventing extubation failure (EF) and related risks to health. We present a novel approach to EF prediction that leverages features classified in free-text respiratory therapy notes using a large language model and logistic regression pipeline. Applied to a patient cohort from University of Washington Medicine, our method identifies clinically meaningful EF-related features that improve EF prediction performance when included alongside structured patient data. We further highlight how differences in target populations in prior EF prediction studies, such as heterogenous inclusion criteria and EF definition, can lead to systematic differences in model performance and hinder generalizability between studies.

In the last decade, Russia's strategic arsenal has pivoted towards a reliance on exotic nuclear-weapon delivery systems. One such system, the Burevestnik (NATO: 9M730) is claimed to be a nuclear-powered, nuclear-armed cruise missile capable of nearly indefinite flight. The air-breathing nuclear propulsion system used in this missile is unique, and its attributes are generally unfamiliar to both the aerospace and nuclear-security communities. To better understand the Burevestnik, and the potential of air-breathing nuclear propulsion systems generally, we have developed a nuclear-aircraft modeling toolkit capable of constraining the missile's performance characteristics. Using this framework, we conclude that the Burevestnik is a subsonic cruise missile system measuring $9.5 \pm 0.32$~m in length, with a $5.6 \pm 0.18$~m wingspan, likely powered by a direct-cycle nuclear turbojet (our calculations almost entirely exclude the possibility of a nuclear ramjet). Under these assumptions, our models predict a reactor thermal power of $4.3\pm 1.3$~MWth at cruise, with peak power demand during climb and terminal maneuvering exceeding $15$~MWth, which may be met with a supplemental chemical interburner. Monte Carlo simulations show that escaping neutrons will generate in excess of 5~TBq of gaseous radionuclides per MW-hr of flight, including isotopes such as $^{41}Ar$, $^{85m}Kr$, $^{83m}Kr$ and $^{14}C$, some of which may be detectable using existing monitoring networks.

In a recent paper [arXiv:2604.24783 (2026)], we have proposed a general approach to treat systems with inherent non-Boltzmann-Gibbsian behaviour. Given the extremely high accuracy of our approach, we have adopted the term hyperstatistics. We have applied such a statistical mechanics approach, i.e., hyperstatistics, to the discharge of a capacitor in a RC series circuit, pumping of $^4$He of a closed cycle cryostat, midrapidity data of $p$-Pb collisions at the LHC, as well as for the distribution of accelerations in turbulent systems. Here, we discuss into more details the ground of hyperstatistics. We demonstrate the versatility of hyperstatistics upon applying it to the velocity autocorrelation function in Brownian motion and also regarding its potential to describe brain dynamics.