Statistics Theory · Cross-listed from cs.GT
A Statistical Analysis of Three Player Auction Bridge
Aritrabha Majumdar, Sourish Sarkar and Moutushi Chatterjee
Three-player Auction Bridge is a finite imperfect-information game in which dynamic partnerships create a distinctive interaction between scoring, strategic incentives, and payoff distribution. This paper develops a unified statistical and game-theoretic framework to evaluate a traditional scoring rule against a modified mechanism designed to improve strategic incentives. We first identify a structural defect in the original scheme: a bid-invariant slam bonus can make lower contracts strictly more attractive than higher ones. A bid-dependent correction removes this incentive distortion. We then compare the two schemes using higher-moment analysis,
fairness measures, Nash
equilibrium analysis, and General-Sum Counterfactual Regret Minimization (GS-CFR). The results show significant differences in the shape of the payoff distributions and reveal that, although both schemes remain highly balanced across physical seats, the modified scheme substantially increases inequality across strategic roles. The game is shown to be neither zero-sum nor constant-sum, motivating a general-sum rather than minimax analysis. Full-game GS-CFR further indicates a substantial increase in the bidder's payoff under the modified scheme, accompanied by a reduction in defender payoff and a shift from separating to partially pooling bidding behavior. These findings demonstrate that scoring-rule design can fundamentally reshape incentives, payoff distribution, and information transmission in imperfect-information games. The proposed framework provides a systematic approach to evaluating such mechanisms from both statistical and strategic perspectives.
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Statistical Methodology · Cross-listed from cs.MA
Multi-dimensional Bias in Modeling Multi-dimensional Preferences: Evaluating the Ability of Synthetic Agents to Replace Human Participants in Conjoint Experiments
Ho Ting Hung, Nachiket Midha, Victor Y. Wu et al. (+1 more)
Despite growing interest in using LLMs to add robustness or reduce data-collection costs in survey experiments, their efficacy in conjoint design—an increasingly popular method in political science—remains underexplored. This paper addresses that gap by investigating whether synthetic
agents can reproduce the multi-dimensional human preference patterns that conjoint is designed to capture. It replicates published conjoint studies and compares the results generated by synthetic
agents with original human data along three dimensions: representational correspondence, inferential correspondence, and procedural stability. Our analysis evaluates the
alignment of choice distributions as well as the statistical and substantive similarity of estimates, and the results are uneven across these dimensions and studies replicated. This implies that the validity of synthetic participants should be considered claim-dependent and hierarchical. Reproducing a figure or obtaining strong sign agreement is evidence of similar aggregate outputs, but not enough to support replacing human respondents. Our results suggest that the discipline as a whole must first map this innovation's boundaries across various levels before considering synthetic
agents a robust substitute for human samples.
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All authors Ho Ting Hung, Nachiket Midha, Victor Y. Wu, Yiwen Zhang
Machine Learning (Statistics) · Cross-listed from cs.LG
Generative Learning of Separatrices
Ellis R. Crabtree, Dimitris G. Giovanis, Anastasia Georgiou et al. (+2 more)
The identification and reconstruction of the boundaries separating basins of attraction in multistable, multidimensional dynamical systems presents a fundamental challenge in computational dynamics. These structures govern transition pathways and other important large timescale behavior, yet they remain typically under-sampled since their neighborhood does not get routinely visited during direct simulations. Traditional computational approaches face computational limitations in high-dimensional systems and require a priori knowledge of the dynamical system and its equations. Simplistic sampling methods such as random or uniform sampling of the phase space typically fail to quantitatively approximate separatrices and their structure altogether. We introduce and implement a framework that combines supervised classification with generative modeling to address this challenge. Our approach first trains neural network classifiers on uniformly or randomly sampled initial conditions labeled by their corresponding basins of attraction in the system of interest. Using uncertainty metrics of the trained classifier to quantify decision boundaries, the method then identifies these high uncertainty regions and boundaries of the classifier as preliminary approximate separatrices. Subsequently, score-based generative models are trained specifically on samples from high-uncertainty regions, ultimately generating densities of samples consistent with the empirical density of samples on or close to the
manifold that constitutes the separatrix between basins in the sampled region. This approach leverages the complementary strengths of (a) discriminative models for global phase space partitioning and (b) generative models for detailed
geometric sampling, resulting in a systematic, iterative, data-driven framework that produces empirically consistent reconstructions of (approximate) separatrix
manifolds.
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All authors Ellis R. Crabtree, Dimitris G. Giovanis, Anastasia Georgiou, George Datseris, Ioannis G. Kevrekidis
Machine Learning (Statistics) · Cross-listed from cs.CR
AccretionLink: On-Device Auditing of Exposure-Control Attacks on Attribute Inference
Faruk Alpay and Taylan Alpay
Exposure control lets an adversary rank authentic public posts to strengthen private-attribute inference without altering content. AccretionLink defines confidentiality and integrity games for this attack, models bounded selection odds through partial identification, and constructs dependence-aware time-uniform e-processes. On 52 held-out synthetic profiles, odds-four selection reduced aggregate negative log likelihood at every horizon. At eight posts the advantage was 0.01595 nats (95% CI [0.00890, 0.02336]), three of four target effects survived Holm adjustment, and label-blind model-guided selection caused 6/109 high-confidence false reversals. On 142 PAN15 test profiles, exploratory selection produced a 0.01227-nat advantage but no reversal. A separate TF-IDF selector retained a 0.01470-nat advantage against the unchanged G5 target, while matched identity shuffling did not reproduce it. Pixel 10 encoded all 1,622 held-out posts once with a fallback-free Tensor G5 graph. A P-256 checkpoint authenticated the selected-replay, actual-model, native-report, and operation digests; local KeyInfo identified the signing key as StrongBox-backed.
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Statistics Theory
Sharp Minimax Theory for Randomized Experiments
Timothy Sudijono, Edgar Dobriban and Eric Tchetgen Tchetgen
We study minimax-optimal designs and
estimators for estimating the sample average treatment effect in finite population randomized experiments, where both design and
estimator are unrestricted. For binary potential outcomes, we show this minimax risk is equivalent to the minimax risk $\rho_n^*$ of an estimation problem with $2$ unknown parameters. We leverage this reduction to establish a second-order risk expansion $\rho_n^* = n^{-1} - Cn^{-4/3} + o_n(n^{-4/3})$ for an explicit constant $C$ related to the Airy function. The minimax risk is attained by Bernoulli randomization with a nonlinear shrinkage
estimator. Our results show that standard procedures such as complete randomization with difference in means are only minimax optimal up to first order in $n.$ We derive further results on admissibility of these procedures and discuss the practical implications of our results.
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Statistics Applications
Joint Temperature-Precipitation Patterns in the U.S. South Central Region: Multivariate Functional Inference and Gaussian Mixture Modeling
Gihani V. W. W. Disanayakage, Asim K. Dey and Kumer P. Das
Joint variability in temperature and precipitation is central in characterizing seasonal
climate structure and associated environmental processes, yet many regional analyses rely on marginal or univariate summaries. We analyze seasonal temperature-precipitation patterns across the Southern United States using two complementary multivariate statistical approaches. First, functional multivariate analysis of variance (FMANOVA) is employed to test the equality of state-level bivariate mean functions, with the permutation-based Wilks' lambda and Pillai's trace statistics. Second, Gaussian mixture models are applied to station-level seasonal summaries to identify latent
climate regimes based on the joint distribution of temperature and precipitation. The FMANOVA results indicate statistically significant differences in bivariate mean trajectories between states in both winter and summer, with seasonal contrasts reflecting differing contributions of temperature and precipitation. Clustering analysis indicates more clearly defined and spatially coherent winter regimes than summer regimes, with summer regimes exhibiting greater variability and a stronger role for precipitation.
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Machine Learning (Statistics)
On the Brittleness of Maximum Likelihood Estimation for Gaussian Process Hyperparameter Optimization
Tyler R. Johnson, Kian Ben-Jacob, Christopher P. Muller et al. (+1 more)
Machine learning (ML) has become an indispensable part of modern engineering design workflows. A crucial step in training an ML model is the selection of the loss function which can be systematically formulated via various techniques such as maximum likelihood estimation (MLE) and cross-validation . While MLE is one of the most popular, effective, and intuitive mechanisms for training ML models, it is brittle: if the assumptions underpinning it are not met, the trained ML model may generalize poorly. This brittleness affects even Gaussian processes (GPs) which are widely used in engineering design and are often (incorrectly) presumed to be very robust to overfitting. In this paper, we fundamentally evaluate the brittleness of MLE in the context of training GPs for probabilistic regression or classification tasks. We compare theoretically grounded metrics against MLE and propose practical solutions. Our extensive studies demonstrate the effectiveness of our solutions in downstream design tasks such as
Bayesian optimization and provide a blueprint for practitioners to build accurate and robust GPs that can even outperform tabular foundation models in terms of prediction accuracy, uncertainty quantification, and inference cost. Our contributions are publicly available via GitHub at https://github.com/Bostanabad-Research-Group/GP-vs-TabPFN-vs-GPyTorch.
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All authors Tyler R. Johnson, Kian Ben-Jacob, Christopher P. Muller, Ramin Bostanabad
Statistical Methodology
Detection of Structural Distortions in Functional Time Series
Debanjana Datta, Rituparna Sen and Nalini Ravishanker
In the era of modern data science, the rapid proliferation of high-dimensional and functional
datasets has fostered increasing interest in the investigation of paradigm shifts and structural breaks. Unlike classical univariate time series, structural changes in functional data need not occur simultaneously across the entire domain; instead, they may emerge locally, producing heterogeneous distortions across the underlying functional structure. The patterns of instability often exhibit sparsity, where it is not known a priori which specific parameters are undergoing a transition. However, in functional contexts, these shifts are often "localised". The difficulty lies in the high dimensionality of the parameter space, where the signal-to-noise ratio may be low for individual components, necessitating the aggregation of information across dimensions to detect a global change. This paper addresses the problem of detecting structural shifts in a functional time series from a
Bayesian perspective. We have developed various novel methodologies that capture the inherent structural distortion in a sequence of random functions, both individually and simultaneously. The formulation of the problem is based on the state-space representation of a functional time series. Efficient Blocked Gibbs Sampling
algorithms have been proposed to identify these locations accurately. Further, we demonstrate the effectiveness of our methods on several financial and temperature
datasets.
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Statistics Applications · Cross-listed from q-bio.NC
Data-driven techniques for translational neuroscience and personalized neuro-health
Vishal Subedi, Shashipraba N. K. Rajakaruna, Pratyusha Sarkar et al. (+10 more)
Neurodegenexrative diseases such as Alzheimer's disease and Parkinson's disease are diagnosed most reliably only after substantial, often irreversible, neuronal loss has already occurred, creating an urgent need for quantitative tools that can detect subtle, early, and individual-specific
brain changes from neuroimaging data. This review surveys a broad and rapidly evolving toolkit of data-driven techniques for translational neuroscience and personalized neuro-health, organized around four complementary methodological pillars. Throughout, we emphasize how these methodologically diverse approaches converge on a common translational goal: personalized, mechanistically grounded, and clinically actionable models of individual
brain health, and we close by discussing the principal open statistical, computational, and clinical challenges that remain.
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All authors Vishal Subedi, Shashipraba N. K. Rajakaruna, Pratyusha Sarkar, Subhankar Chattoraj, Anjali Khasa, Siddhartha Nandy, Hamza Farooq, Animikh Biswas, Sanjay Chaudhuri, Asim K. Dey, Karuna Joshi, Christophe Lenglet, Ansu Chatterjee
Statistics Theory · Cross-listed from math.PR
Graph Causal Optimal Transport and Wasserstein Distances
Jan Obłój and Vlad Tuchilus
We study the graph causal optimal transport problem, a generalisation of the classical optimal transport problem in which the allowed couplings satisfy causal restrictions prescribed by a directed graph. We characterise fully the directed acyclic graphs for which the associated graph causal Wasserstein discrepancy is a metric and show that the induced
topology agrees with other natural adapted
topologies. We characterise the gluing properties of graph causal couplings, prove denseness of Monge couplings, and obtain a dynamic programming principle which allows us to deduce when the graph causal Wasserstein and the adapted Wasserstein distances are equal. Our results link fundamental properties of graph causal optimal transport to structural properties of its underlying graph. Complementing Cheridito and Eckstein (2025), who first introduced such distances and established Lipschitz continuity for the average treatment effect in structural causal models, we obtain Lipschitz continuity of the value function in
stochastic team problems.
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Statistical Methodology
Hyperbolic Latent Position Models for Hierarchical Bipartite Data
Kisung You
Binary bipartite data often combine row and column heterogeneity with hierarchical interaction, as when students answer exercises organized by prerequisites or legislators vote on nested policy areas. Fixed-dimensional Euclidean volume grows only polynomially with radius, whereas branching hierarchies expand exponentially.
Hyperbolic space matches this growth, and its rooted Gromov product measures shared ancestry. We propose the
HypErbolic Latent Position model for bipartite Interaction data (HELPI), which places both object types in
hyperbolic space while separating
geometric interaction from additive propensities. With unrestricted main effects, a
hyperbolic-distance predictor is likelihood-equivalent to a rooted Gromov-product predictor. Radial depth is absorbed by additive terms, leaving a root-invariant projected hierarchy signal as the identified
geometric target. We establish identification and posterior contraction results and develop augmented variational procedures for binary outcomes. Simulations support recovery of hierarchical interaction and clarify weak-branch regimes. In Junyi Academy data, curriculum anchors yield an interpretable geometry with temporal prediction close to item-response
benchmarks, while distinguishing attempted exercises from unconditional mastery. In U.S. House roll calls, flexible HELPI variants improve on additive and two-parameter logistic
benchmarks and recover party and policy structure without using party labels during fitting.
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Statistical Methodology
Nonprobability Samples for Small Area Estimation: A Review and Comparative Simulation Study
Sho Kawano, Daniel Vedensky, Qianyu Dong et al. (+5 more)
Nonprobability samples (NPS) are attractive because they are less costly to collect, can provide substantially larger sample sizes, and may reach populations that traditional probability surveys do not. As response rates for traditional surveys fall, interest in NPS has grown rapidly within the field of survey statistics. These methods are especially relevant for small area estimation (SAE), where there is ever-present demand for estimates at fine geographic scales and detailed demographic domains. Despite rapid methodological development, there remains limited understanding of which approaches perform best under different conditions. In this paper, we review recent developments in NPS methodology, including the concept of data defect correlation (DDC) as a measure of data quality and as a tool for categorizing the various NPS methods. We then present a comprehensive simulation study that evaluates a range of NPS approaches under varying levels of DDC and extend several existing methods to the SAE setting.
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All authors Sho Kawano, Daniel Vedensky, Qianyu Dong, Ethan Pawl, Qi Wang, Paul A. Parker, Zehang Richard Li, Scott H. Holan
Statistical Methodology
Bias Reduction for Local Polynomial Derivative Estimation
Fujia Chang and W. John Braun
Local
polynomial smoothing is commonly used in non-parametric regression, but local linear derivative estimation still has a bias of order $O(h^2)$. This paper proposes an iterative data sharpening method to reduce the bias of derivative estimates while retaining the simplicity of local linear fitting. The method is based on two expectation operators: $L_0$, acting on the regression function, and $L_1$, acting on the first-order derivative. By repeatedly applying the residual operator $R=I-L_0$, a series of sharpened derivative estimates can be constructed. After $l$ sharpening steps, the bias order can be reduced from $O(h^2)$ to $O(h^{2l+2})$. For the Gaussian kernel, all sharpening coefficients equal 1, giving a simple closed-form single-bandwidth expression. Simulation experiments on three smooth test functions show that this method can significantly reduce the estimation bias while revealing a bias-variance trade-off.
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Statistics Applications
Small Area Estimation under Spatial Regimes: Spatially Clustered Fay-Herriot Models for Agricultural Indicators
Paolo Maranzano, Raffaele Mattera and Shonosuke Sugasawa
Area-level small area estimation (SAE) models, such as the Fay–Herriot (FH) model, borrow strength across domains through
covariates and random effects, but they can struggle when the relationship between the
covariates and the outcome is spatially heterogeneous, that is, when it changes across the spatial domain of interest. We propose a spatially-clustered FH (SC-FH) framework that simultaneously (i) estimates cluster-specific regression coefficients and random effects variances and (ii) generates spatially coherent partitions of the geographical domain. Estimation maximizes a penalized likelihood that augments the FH likelihood with a Potts-type spatial cohesion term over the areal adjacency graph, through an efficient strategy that alternates between sequential label updates and closed-form FH updates within clusters. In simulation experiments run on the real geography of the application, the method recovers the latent regimes almost exactly whenever they are separated in the
covariate–response space and improves prediction accuracy over the standard FH
benchmark, with the spatial penalty acting as a stabilizer of both classification and estimation. An empirical application to the average standard output of farms in the Po Valley (Northern Italy) identifies two spatially compact production regimes with significantly different cluster-wise coefficients, and shows that the clusterwise predictor improves on the direct estimates while avoiding the over-shrinkage of the pooled model.
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Machine Learning (Statistics)
Learning Unsteady Aneurysm Hemodynamics with Physics-Informed DeepONets
Oscar L. Cruz-Gonzalez, Valérie Deplano and Badih Ghattas
Clinically actionable, patient-specific hemodynamic assessment, specifically wall shear stress,
vortex structure and pressure distributions, is critical for determining risky or unfavorable
evolution in Abdominal Aortic Aneurysms (AAA). While Physics-Informed Deep Operator Networks (PI-DeepONets) show promising results in complementing established 5 tools such as Computational Fluid Dynamics (CFD), a persistent architectural challenge remains for complex 3D flows. In this direction, we propose a Modified Multi-Input Multi-Output PI-DeepONets (M3PI-DeepONet) designed for predicting unsteady flows in an idealized AAA geometry. Central to our model is the Aggregated Injection strategy, where latent representations from multiple input branches are fused prior to trunk injection, allowing the coordinate basis to adapt to multiple physical constraints. To the best of our knowledge, this is the first architecture to combine the layer-wise gating mechanism with a multi-branch operator-network
topology, yielding an input-adaptive trunk basis. Additionally, we integrate the 3D Navier-Stokes equations as governing physical laws, so the model is trained based on physics-informed residuals, initial and boundary conditions, and only 0.3% of the labeled internal data together with the selected branch-conditioning signals. The M3PI-DeepONet simultaneously predicts unsteady 3D flow velocity and pressure fields with an average relative L2 velocity error below 4% and pressure error around 5% while achieving a conservative retained-cycle inference speedup of approximately 36x compared to reference CFD simulations once the branch inputs used for conditioning are available. This work advances the application of deep learning in cardiovascular disease modeling, marking step toward real-time, non-invasive clinical diagnostics.
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Machine Learning (Statistics) · Cross-listed from cs.LG
Defensive Boosting for Online Probabilistic Forecasting
Georgy Noarov and Aaron Roth
We study online probabilistic forecasting of binary outcomes chosen by an adaptive adversary. Given an online learning
algorithm for a weak hypothesis class $H$, we would like to efficiently obtain two incomparable guarantees that existing online boosting techniques provide separately. Online gradient boosting competes in Brier score with the best predictor induced by the span of $H$ on every sequence, but promises nothing when the span does not contain an accurate predictor. Online weak-to-strong boosting drives classification error to zero under a weak-learning condition, but promises little when that condition fails. We give a simple defensive forecasting
algorithm, the Defensive Booster, that obtains both guarantees. On every adaptive sequence, its Brier score is competitive with the best prediction induced by the span of $H$ at the same rate as online gradient boosting; simultaneously, whenever the realized transcript satisfies the smooth weak-learning condition, its Brier score and randomized classification error satisfy the same rate guarantee as online classification boosting. This is achieved by operationalizing the "dual view" of boosting: When the
algorithm's randomized classification error is persistently high, its mistake weights form a smooth reweighting on which every weak hypothesis has low edge, yielding an ex-post hard-core certificate that the weak-learning condition fails. We also develop a strongly adaptive variant, which satisfies both guarantees on every time interval. The Defensive Booster is very efficient: it accesses just one weak-class learner, whereas the prior online boosting methods we compare against maintain large weak-learner ensembles. Experiments on synthetic and real data streams demonstrate its strong predictive performance (sometimes substantially improving over all prior baselines) coupled with orders-of-magnitude faster runtime.
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Machine Learning (Statistics) · Cross-listed from cs.LG
Exponential Convex Calibration Dimension for the Multi-Label Jaccard Measure
Mingyuan Zhang
The per-instance Jaccard score, or intersection over union (IoU), is standard in multi-label classification and binary segmentation. With $s$ labels, its loss
matrix has $2^s$ outcomes and reports. Under the convention $\mathrm{Jac}(\varnothing,\varnothing)=1$, we prove that the Jaccard score, shifted-loss, and ordinary loss
matrices are nonsingular and that the loss columns have affine dimension $2^s-1$. The proof combines a finite MinHash Gram representation with Boolean Möbius inversion. For exact calibration, we prove $2^{s-1} \leq \mathrm{CCdim}(L^{\mathrm{Jac}}) \leq 2^s-1$. The lower bound uses a factorially weighted distribution with $2^{s-1}+1$ supported outcomes and Bayes-optimal reports. Consequently, every exactly calibrated convex surrogate requires exponentially many prediction coordinates. We also give two
polynomial-dimensional approximation guarantees with explicit regret transfers. A new $F_1$-to-Jaccard transfer turns an existing $(s^2+1)$-dimensional $F_1$ surrogate into a
polynomial-time rule with asymptotic Jaccard regret at most $3-2\sqrt{2}$. For any $\alpha>0$ and $0<\rho<1$, a MinHash square-loss surrogate attains Jaccard-regret floor $\alpha$ uniformly over arbitrary conditional label distributions. With probability at least $1-\rho$, the direct construction has dimension $O((s^2+s\log(1/\rho))/\alpha^2)$, while a signed variant has dimension $O((s+\log(1/\rho))/\alpha^2)$. Thus zero-regret calibration requires exponential dimension, whereas every fixed additive regret tolerance admits
polynomial prediction dimension.
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Statistics Theory · Cross-listed from cs.LG
The data geometry of masking diffusion: Certified-optimal schedules via unmasking growth complexity
Martin J. Wainwright
We study masking
diffusion for discrete sampling and introduce a path-resolved measure of data geometry called the unmasking growth complexity ({UGC\xspace}). Its local increments directly control Kullback–Leibler (KL) discretization error, yielding a unified analysis of Bernoulli-subset and fixed-cardinality unmasking schemes. In log-reveal-odds coordinates, this structure yields optimized single-block and multi-block schedules, and quantifies the gains from adapting computational effort to data geometry. Crucially, we show how {UGC\xspace} increments can be estimated from samples via KL increments along coupled reveal trajectories. This leads to certified-optimal samplers that achieve a prescribed KL error with high probability and iteration complexity within a constant factor of the corresponding oracle procedure. Collapsing the \ugc path yields the aggregate {UGC\xspace} mass, which connects to classical multivariate dependence measures and complexity measures from previous analyses of discrete
diffusion. In the fine-partition limit, the squared integral of the square-root {UGC\xspace} density determines the sharp leading-order optimal Euler discretization error. Examples exhibit substantial dimension-dependent gains over coarse schedules, including $\widetilde{\Omega}(\sqrt{d})$ improvements achievable with a constant number of adaptively placed blocks.
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Machine Learning (Statistics)
Bagging Robustly Learns VC Classes with Linear Sample Complexity
Omar Montasser
We revisit the problem of learning predictors robust to
adversarial examples at test-time. We prove that VC classes are adversarially robustly learnable with sample complexity linear in the VC dimension $d$, providing an exponential improvement over the previous upper bound of Montasser, Hanneke, and Srebro (2019). Remarkably, this result is achieved with a simple improper
algorithm that combines the classic heuristic bagging (bootstrap aggregation) of Breiman (1996) with robust empirical risk minimization (RERM). Our
algorithm computes RERMs on $O(d^\star)$ independent bootstrap samples and outputs their majority vote, where $d^\star$ denotes the dual VC dimension. We complement this result with a lower bound showing that this is unavoidable: in general, any learner in this oracle model requires $\Omega(d^\star)$ calls to an RERM oracle, even when given arbitrarily many training examples.
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Statistics Theory
On the Structural Limits of Machine Learning Decision Systems: An Information-Theoretic, Interaction-Based, and Stochastic-Dynamical Perspective
Nestor R. Barraza and Gabriel Pena
Machine learning procedures are commonly evaluated in terms of predictive accuracy and computational efficiency. However, their achievable performance is fundamentally constrained by structural properties of the underlying data-generating process, which are formalized in terms of informational bounds. In this work we examine intrinsic limits of data-driven decision systems from an information-theoretic and interaction-based perspective. We analyze minimal achievable error in classification through Fano-type bounds and precision limits in parametric estimation via the Cramér-Rao inequality, emphasizing that such limits depend on the underlying model rather than on algorithmic sophistication alone. We further discuss how implicit assumptions, such as independence, ergodicity, and distributional stability, affect the validity of inferential procedures. Building on interaction-based modeling principles, we review typical frameworks such as Markov Random Fields and potential based representations for encoding dependence mechanisms. We also describe decision systems, including LLM-integrated
agent architectures, as feedback-driven
stochastic processes where state-dependent dynamics may induce emergent macroscopic behavior. This perspective highlights the importance of having adequate models for the data as a prerequi- site for expanding predictive capability, and situates algorithmic learning within the informational limits imposed by the models.
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Statistical Methodology
Theoretical Properties of Covariate-Adaptive Randomization with a Diverging Number of Covariates
Yuhang Tao and Li-Xin Zhang
Covariate-adaptive randomization procedures are widely used in clinical trials to improve
covariate balance. In modern applications, experimenters often have access to many
covariates, motivating the need for a theory of
covariate-adaptive randomization procedures with a diverging number of
covariates. This paper studies two classes of
covariate-adaptive randomization procedures, referred to as imbalance-efficient
covariate-adaptive randomization and imbalance-robust
covariate-adaptive randomization, when the feature dimension diverges. We derive convergence rates for the imbalance of the
covariates used in randomization. For both procedures, the imbalance is of a smaller order than that under complete randomization when the feature dimension is $o(n)$, whereas it is of the same order when the feature dimension is $\Omega(n)$. For imbalance-robust
covariate-adaptive randomization, we further establish the asymptotic properties of the imbalance of additional
covariates and use these results to derive the asymptotic distribution of the difference-in-means
estimator for the average treatment effect and construct asymptotically valid confidence intervals. Furthermore, we provide extensive numerical and empirical studies to illustrate the practical relevance of our theoretical results.
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