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Sunday 18 January

Statistics Applications

Analyzing the Temporal Factors for Anxiety and Depression Symptoms with the Rashomon Perspective

This paper introduces a new modeling perspective in the public mental health domain to provide a robust interpretation of the relations between anxiety and depression, and the demographic and temporal factors. This perspective particularly leverages the Rashomon Effect, where multiple models exhibit similar predictive performance but rely on diverse internal structures. Instead of considering these multiple models, choosing a single best model risks masking alternative narratives embedded in the data. To address this, we employed this perspective in the interpretation of a large-scale psychological dataset, specifically focusing on the Patient Health Questionnaire-4. We use a random forest model combined with partial dependence profiles to rigorously assess the robustness and stability of predictive relationships across the resulting Rashomon set, which consists of multiple models that exhibit similar predictive performance. Our findings confirm that demographic variables age, sex, and education lead to consistent structural shifts in anxiety and depression risk. Crucially, we identify significant temporal effects: risk probability demonstrates clear diurnal and circaseptan fluctuations, peaking during early morning hours. This work demonstrates the necessity of moving beyond the best model to analyze the entire Rashomon set. Our results highlight that the observed variability, particularly due to circadian and circaseptan rhythms, must be meticulously considered for robust interpretation in psychological screening. We advocate for a multiplicity-aware approach to enhance the stability and generalizability of ML-based conclusions in mental health research.
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All authors Mustafa Cavus, Przemysław Biecek, Julian Tejada, Fernando Marmolejo-Ramos, Andre Faro

Machine Learning (Statistics) · Cross-listed from cs.LG

What Trace Powers Reveal About Log-Determinants: Closed-Form Estimators, Certificates, and Failure Modes

Computing $\log\det(A)$ for large symmetric positive definite matrices arises in Gaussian process inference and Bayesian model comparison. Standard methods combine matrix-vector products with polynomial approximations. We study a different model: access to trace powers $p_k = \tr(A^k)$, natural when matrix powers are available. Classical moment-based approximations Taylor-expand $\log(\lambda)$ around the arithmetic mean. This requires $|\lambda - \AM| < \AM$ and diverges when $\kappa > 4$. We work instead with the moment-generating function $M(t) = \E[X^t]$ for normalized eigenvalues $X = \lambda/\AM$. Since $M'(0) = \E[\log X]$, the log-determinant becomes $\log\det(A) = n(\log \AM + M'(0))$ – the problem reduces to estimating a derivative at $t = 0$. Trace powers give $M(k)$ at positive integers, but interpolating $M(t)$ directly is ill-conditioned due to exponential growth. The transform $K(t) = \log M(t)$ compresses this range. Normalization by $\AM$ ensures $K(0) = K(1) = 0$. With these anchors fixed, we interpolate $K$ through $m+1$ consecutive integers and differentiate to estimate $K'(0)$. However, this local interpolation cannot capture arbitrary spectral features. We prove a fundamental limit: no continuous estimator using finitely many positive moments can be uniformly accurate over unbounded conditioning. Positive moments downweight the spectral tail; $K'(0) = \E[\log X]$ is tail-sensitive. This motivates guaranteed bounds. From the same traces we derive upper bounds on $(\det A)^{1/n}$. Given a spectral floor $r \leq \lambda_{\min}$, we obtain moment-constrained lower bounds, yielding a provable interval for $\log\det(A)$. A gap diagnostic indicates when to trust the point estimate and when to report bounds. All estimators and bounds cost $O(m)$, independent of $n$. For $m \in \{4, \ldots, 8\}$, this is effectively constant time.
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Machine Learning (Statistics)

A Theory of Diversity for Random Matrices with Applications to In-Context Learning of Schrödinger Equations

We address the following question: given a collection $\{\mathbf{A}^{(1)}, \dots, \mathbf{A}^{(N)}\}$ of independent $d \times d$ random matrices drawn from a common distribution $\mathbb{P}$, what is the probability that the centralizer of $\{\mathbf{A}^{(1)}, \dots, \mathbf{A}^{(N)}\}$ is trivial? We provide lower bounds on this probability in terms of the sample size $N$ and the dimension $d$ for several families of random matrices which arise from the discretization of linear Schrödinger operators with random potentials. When combined with recent work on machine learning theory, our results provide guarantees on the generalization ability of transformer-based neural networks for in-context learning of Schrödinger equations.
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Statistics Theory · Cross-listed from econ.EM

Partial Identification under Stratified Randomization

This paper develops a unified framework for partial identification and inference in stratified experiments with attrition, accommodating both equal and heterogeneous treatment shares across strata. For equal-share designs, we apply recent theory for finely stratified experiments to Lee bounds, yielding closed-form, design-consistent variance estimators and properly sized confidence intervals. Simulations show that the conventional formula can overstate uncertainty, while our approach delivers tighter intervals. When treatment shares differ across strata, we propose a new strategy, which combines inverse probability weighting and global trimming to construct valid bounds even when strata are small or unbalanced. We establish identification, introduce a moment estimator, and extend existing inference results to stratified designs with heterogeneous shares, covering a broad class of moment-based estimators which includes the one we formulate. We also generalize our results to designs in which strata are defined solely by observed labels.
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Statistics Applications

Stop using limiting stimuli as a measure of sensitivities of energetic materials

Accurately estimating the sensitivity of explosive materials is a potentially life-saving task which requires standardised protocols across nations. One of the most widely applied procedures worldwide is the so-called '1-In-6' test from the United Nations (UN) Manual of Tests in Criteria, which estimates a 'limiting stimulus' for a material. In this paper we demonstrate that, despite their popularity, limiting stimuli are not a well-defined notion of sensitivity and do not provide reliable information about a material's susceptibility to ignition. In particular, they do not permit construction of confidence intervals to quantify estimation uncertainty. We show that continued reliance on limiting stimuli through the 1-In-6 test has caused needless confusion in energetic materials research, both in theoretical studies and practical safety applications. To remedy this problem, we consider three well-founded alternative approaches to sensitivity testing to replace limiting stimulus estimation. We compare their performance in an extensive simulation study and apply the best-performing approach to real data, estimating the friction sensitivity of pentaerythritol tetranitrate (PETN).
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Statistical Methodology

Rerandomization for quantile treatment effects

Although complete randomization is widely regarded as the gold standard for causal inference, covariate imbalance can still arise by chance in finite samples. Rerandomization has emerged as an effective tool to improve covariate balance across treatment groups and enhance the precision of causal effect estimation. While existing work focuses on average treatment effects, quantile treatment effects (QTEs) provide a richer characterization of treatment heterogeneity by capturing distributional shifts in outcomes, which is crucial for policy evaluation and equity-oriented research. In this article, we establish the asymptotic properties of the QTE estimator under rerandomization within a finite-population framework, without imposing any distributional or modeling assumptions on the covariates or outcomes.The estimator exhibits a non-Gaussian asymptotic distribution, represented as a linear combination of Gaussian and truncated Gaussian random variables. To facilitate inference, we propose a conservative variance estimator and construct corresponding confidence interval. Our theoretical analysis demonstrates that rerandomization improves efficiency over complete randomization under mild regularity conditions. Simulation studies further support the theoretical findings and illustrate the practical advantages of rerandomization for QTE estimation.
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Machine Learning (Statistics) · Cross-listed from cs.LG

Cooperative Multi-agent RL with Communication Constraints

Cooperative MARL often assumes frequent access to global information in a data buffer, such as team rewards or other agents' actions, which is typically unrealistic in decentralized MARL systems due to high communication costs. When communication is limited, agents must rely on outdated information to estimate gradients and update their policies. A common approach to handle missing data is called importance sampling, in which we reweigh old data from a base policy to estimate gradients for the current policy. However, it quickly becomes unstable when the communication is limited (i.e. missing data probability is high), so that the base policy in importance sampling is outdated. To address this issue, we propose a technique called base policy prediction, which utilizes old gradients to predict the policy update and collect samples for a sequence of base policies, which reduces the gap between the base policy and the current policy. This approach enables effective learning with significantly fewer communication rounds, since the samples of predicted base policies could be collected within one communication round. Theoretically, we show that our algorithm converges to an $\varepsilon$-Nash equilibrium in potential games with only $O(\varepsilon^{-3/4})$ communication rounds and $O(poly(\max_i |A_i|)\varepsilon^{-11/4})$ samples, improving existing state-of-the-art results in communication cost, as well as sample complexity without the exponential dependence on the joint action space size. We also extend these results to general Markov Cooperative Games to find an agent-wise local maximum. Empirically, we test the base policy prediction algorithm in both simulated games and MAPPO for complex environments.
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Statistical Computation

Bayesian Inference for Partially Observed McKean-Vlasov SDEs with Full Distribution Dependence

McKean-Vlasov stochastic differential equations (MVSDEs) describe systems whose dynamics depend on both individual states and the population distribution, and they arise widely in neuroscience, finance, and epidemiology. In many applications the system is only partially observed, making inference very challenging when both drift and diffusion coefficients depend on the evolving empirical law. This paper develops a Bayesian framework for latent state inference and parameter estimation in such partially observed MVSDEs. We combine time-discretization with particle-based approximations to construct tractable likelihood estimators, and we design two particle Markov chain Monte Carlo (PMCMC) algorithms: a single-level PMCMC method and a multilevel PMCMC (MLPMCMC) method that couples particle systems across discretization levels. The multilevel construction yields correlated likelihood estimates and achieves mean square error $(O(\varepsilon^2))$ at computational cost $(O(\varepsilon^{-6}))$, improving on the $(O(\varepsilon^{-7}))$ complexity of single-level schemes. We address the fully law-dependent diffusion setting which is the most general formulation of MVSDEs, and provide theoretical guarantees under standard regularity assumptions. Numerical experiments confirm the efficiency and accuracy of the proposed methodology.
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Statistics Applications

Assessing Interactive Causes of an Occurred Outcome Due to Two Binary Exposures

In contrast to evaluating treatment effects, causal attribution analysis focuses on identifying the key factors responsible for an observed outcome. For two binary exposure variables and a binary outcome variable, researchers need to assess not only the likelihood that an observed outcome was caused by a particular exposure, but also the likelihood that it resulted from the interaction between the two exposures. For example, in the case of a male worker who smoked, was exposed to asbestos, and developed lung cancer, researchers aim to explore whether the cancer resulted from smoking, asbestos exposure, or their interaction. Even in randomized controlled trials, widely regarded as the gold standard for causal inference, identifying and evaluating retrospective causal interactions between two exposures remains challenging. In this paper, we define posterior probabilities to characterize the interactive causes of an observed outcome. We establish the identifiability of posterior probabilities by using a secondary outcome variable that may appear after the primary outcome. We apply the proposed method to the classic case of smoking and asbestos exposure. Our results indicate that for lung cancer patients who smoked and were exposed to asbestos, the disease is primarily attributable to the synergistic effect between smoking and asbestos exposure.
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All authors Shanshan Luo, Wei Li, Xueli Wang, Shaojie Wei, Zhi Geng

Statistical Methodology

Robust semi-parametric mixtures of linear experts using the contaminated Gaussian distribution

Semi- and non-parametric mixture of regressions are a very useful flexible class of mixture of regressions in which some or all of the parameters are non-parametric functions of the covariates. These models are, however, based on the Gaussian assumption of the component error distributions. Thus, their estimation is sensitive to outliers and heavy-tailed error distributions. In this paper, we propose semi- and non-parametric contaminated Gaussian mixture of regressions to robustly estimate the parametric and/or non-parametric terms of the models in the presence of mild outliers. The virtue of using a contaminated Gaussian error distribution is that we can simultaneously perform model-based clustering of observations and model-based outlier detection. We propose two algorithms, an expectation-maximization (EM)-type algorithm and an expectation-conditional-maximization (ECM)-type algorithm, to perform maximum likelihood and local-likelihood kernel estimation of the parametric and non-parametric of the proposed models, respectively. The robustness of the proposed models is examined using an extensive simulation study. The practical utility of the proposed models is demonstrated using real data.
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Machine Learning (Statistics) · Cross-listed from cs.LG

Statistical-Neural Interaction Networks for Interpretable Mixed-Type Data Imputation

Real-world tabular databases routinely combine continuous measurements and categorical records, yet missing entries are pervasive and can distort downstream analysis. We propose Statistical-Neural Interaction (SNI), an interpretable mixed-type imputation framework that couples correlation-derived statistical priors with neural feature attention through a Controllable-Prior Feature Attention (CPFA) module. CPFA learns head-wise prior-strength coefficients $\{\lambda_h\}$ that softly regularize attention toward the prior while allowing data-driven deviations when nonlinear patterns appear to be present in the data. Beyond imputation, SNI aggregates attention maps into a directed feature-dependency matrix that summarizes which variables the imputer relied on, without requiring post-hoc explainers. We evaluate SNI against six baselines (Mean/Mode, MICE, KNN, MissForest, GAIN, MIWAE) on six datasets spanning ICU monitoring, population surveys, socio-economic statistics, and engineering applications. Under MCAR/strict-MAR at 30% missingness, SNI is generally competitive on continuous metrics but is often outperformed by accuracy-first baselines (MissForest, MIWAE) on categorical variables; in return, it provides intrinsic dependency diagnostics and explicit statistical-neural trade-off parameters. We additionally report MNAR stress tests (with a mask-aware variant) and discuss computational cost, limitations – particularly for severely imbalanced categorical targets – and deployment scenarios where interpretability may justify the trade-off.
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All authors Ou Deng, Shoji Nishimura, Atsushi Ogihara, Qun Jin

Statistical Methodology

Single-index Semiparametric Transformation Cure Models with Interval-censored Data

Interval censored data commonly arise in medical studies when the event time of interest is only known to lie within an interval. In the presence of a cure subgroup, conventional mixture cure models typically assume a logistic model for the uncure probability and a proportional hazards model for the susceptible subjects. However, in practice, the assumptions of parametric form for the uncure probability and the proportional hazards model for the susceptible may not always be satisfied. In this paper, we propose a class of flexible single-index semiparametric transformation cure models for interval-censored data, where a single-index model and a semiparametric transformation model are utilized for the uncured and conditional survival probability, respectively, encompassing both the proportional hazards cure and proportional odds cure models as specific cases. We approximate the single-index function and cumulative baseline hazard functions via the kernel technique and splines, respectively, and develop a computationally feasible expectation-maximisation (EM) algorithm, facilitated by a four-layer gamma-frailty Poisson data augmentation. Simulation studies demonstrate the satisfactory performance of our proposed method, compared to the spline-based approach and the classical logistic-based mixture cure models. The application of the proposed methodology is illustrated using the Alzheimers dataset.
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Machine Learning (Statistics) · Cross-listed from econ.EM

How Well Do LLMs Predict Human Behavior? A Measure of their Pretrained Knowledge

Large language models (LLMs) are increasingly used to predict human behavior. We propose a measure for evaluating how much knowledge a pretrained LLM brings to such a prediction: its equivalent sample size, defined as the amount of task-specific data needed to match the predictive accuracy of the LLM. We estimate this measure by comparing the prediction error of a fixed LLM in a given domain to that of flexible machine learning models trained on increasing samples of domain-specific data. We further provide a statistical inference procedure by developing a new asymptotic theory for cross-validated prediction error. Finally, we apply this method to the Panel Study of Income Dynamics. We find that LLMs encode considerable predictive information for some economic variables but much less for others, suggesting that their value as substitutes for domain-specific data differs markedly across settings.
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Statistics Applications

A Machine Learning–Based Surrogate EKMA Framework for Diagnosing Urban Ozone Formation Regimes: Evidence from Los Angeles

Surface ozone pollution remains a persistent challenge in many metropolitan regions worldwide, as the nonlinear dependence of ozone formation on nitrogen oxides and volatile organic compounds (VOCs) complicates the design of effective emission control strategies. While chemical transport models provide mechanistic insights, they rely on detailed emission inventories and are computationally expensive. This study develops a machine learning–based surrogate framework inspired by the Empirical Kinetic Modeling Approach (EKMA). Using hourly air quality observations from Los Angeles during 2024–2025, a random forest model is trained to predict surface ozone concentrations based on precursor measurements and spatiotemporal features, including site location and cyclic time encodings. The model achieves strong predictive performance, with permutation importance highlighting the dominant roles of diurnal temporal features and nitrogen dioxide, along with additional contributions from carbon monoxide. Building on the trained surrogate, EKMA-style sensitivity experiments are conducted by perturbing precursor concentrations while holding other covariates fixed. The results indicate that ozone formation in Los Angeles during the study period is predominantly VOC-limited. Overall, the proposed framework offers an efficient and interpretable approach for ozone regime diagnosis in data-rich urban environments.
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Machine Learning (Statistics)

On the Provable Suboptimality of Momentum SGD in Nonstationary Stochastic Optimization

In this paper, we provide a comprehensive theoretical analysis of Stochastic Gradient Descent (SGD) and its momentum variants (Polyak Heavy-Ball and Nesterov) for tracking time-varying optima under strong convexity and smoothness. Our finite-time bounds reveal a sharp decomposition of tracking error into transient, noise-induced, and drift-induced components. This decomposition exposes a fundamental trade-off: while momentum is often used as a gradient-smoothing heuristic, under distribution shift it incurs an explicit drift-amplification penalty that diverges as the momentum parameter $\beta$ approaches 1, yielding systematic tracking lag. We complement these upper bounds with minimax lower bounds under gradient-variation constraints, proving this momentum-induced tracking penalty is not an analytical artifact but an information-theoretic barrier: in drift-dominated regimes, momentum is unavoidably worse because stale-gradient averaging forces systematic lag. Our results provide theoretical grounding for the empirical instability of momentum in dynamic settings and precisely delineate regime boundaries where vanilla SGD provably outperforms its accelerated counterparts.
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Statistical Computation · Cross-listed from cs.LG

Wavelet-Aware Anomaly Detection in Multi-Channel User Logs via Deviation Modulation and Resolution-Adaptive Attention

Insider threat detection is a key challenge in enterprise security, relying on user activity logs that capture rich and complex behavioral patterns. These logs are often multi-channel, non-stationary, and anomalies are rare, making anomaly detection challenging. To address these issues, we propose a novel framework that integrates wavelet-aware modulation, multi-resolution wavelet decomposition, and resolution-adaptive attention for robust anomaly detection. Our approach first applies a deviation-aware modulation scheme to suppress routine behaviors while amplifying anomalous deviations. Next, discrete wavelet transform (DWT) decomposes the log signals into multi-resolution representations, capturing both long-term trends and short-term anomalies. Finally, a learnable attention mechanism dynamically reweights the most discriminative frequency bands for detection. On the CERT r4.2 benchmark, our approach consistently outperforms existing baselines in precision, recall, and F1 score across various time granularities and scenarios.
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All authors Kaichuan Kong, Dongjie Liu, Xiaobo Jin, Shijie Xu, Guanggang Geng

2601.12231 · 18 Jan · Accepted by ICASSP 2026. Copyright 2026 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works

Statistics Applications

A warping function-based control chart for detecting distributional changes in damage-sensitive features for structural condition assessment

Data-driven damage detection methods achieve damage identification by analyzing changes in damage-sensitive features (DSFs) derived from structural health monitoring (SHM) data. The core reason for their effectiveness lies in the fact that damage or structural state transition can be manifested as changes in the distribution of DSF data. This enables us to reframe the problem of damage detection as one of identifying these distributional changes. Hence, developing automated tools for detecting such changes is pivotal for automated structural health diagnosis. Control charts are extensively utilized in SHM for DSF change detection, owing to their excellent online detection and early warning capabilities. However, conventional methods are primarily designed to detect mean or variance shifts, making it challenging to identify complex shape changes in distributions. This limitation results in insufficient damage detection sensitivity. Moreover, they typically exhibit poor robustness against data contamination. This paper proposes a novel control chart to address these limitations. It employs the probability density functions (PDFs) of subgrouped DSF data as monitoring objects, with shape deformations characterized by warping functions. Furthermore, a nonparametric control chart is specifically constructed for warping function monitoring in the functional data analysis framework. Key advantages of the new method include the ability to detect both shifts and complex shape deformations in distributions, excellent online detection performance, and robustness against data contamination. Extensive simulation studies demonstrate its superiority over competing approaches. Finally, the method is applied to detecting distributional changes in DSF data for cable condition assessment in a long-span cable-stayed bridge, demonstrating its practical utility in engineering.
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Machine Learning (Statistics) · Cross-listed from cs.LG

One-Sided Matrix Completion from Ultra-Sparse Samples

Matrix completion is a classical problem that has received recurring interest across a wide range of fields. In this paper, we revisit this problem in an ultra-sparse sampling regime, where each entry of an unknown, $n\times d$ matrix $M$ (with $n \ge d$) is observed independently with probability $p = C / d$, for a fixed integer $C \ge 2$. This setting is motivated by applications involving large, sparse panel datasets, where the number of rows far exceeds the number of columns. When each row contains only $C$ entries – fewer than the rank of $M$ – accurate imputation of $M$ is impossible. Instead, we estimate the row span of $M$ or the averaged second-moment matrix $T = M^{\top} M / n$. The empirical second-moment matrix computed from observed entries exhibits non-random and sparse missingness. We propose an unbiased estimator that normalizes each nonzero entry of the second moment by its observed frequency, followed by gradient descent to impute the missing entries of $T$. The normalization divides a weighted sum of $n$ binomial random variables by the total number of ones. We show that the estimator is unbiased for any $p$ and enjoys low variance. When the row vectors of $M$ are drawn uniformly from a rank-$r$ factor model satisfying an incoherence condition, we prove that if $n \ge O({d r^5 \epsilon^{-2} C^{-2} \log d})$, any local minimum of the gradient-descent objective is approximately global and recovers $T$ with error at most $\epsilon^2$. Experiments on both synthetic and real-world data validate our approach. On three MovieLens datasets, our algorithm reduces bias by $88\%$ relative to baseline estimators. We also empirically validate the linear sampling complexity of $n$ relative to $d$ on synthetic data. On an Amazon reviews dataset with sparsity $10^{-7}$, our method reduces the recovery error of $T$ by $59\%$ and $M$ by $38\%$ compared to baseline methods.
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All authors Hongyang R. Zhang, Zhenshuo Zhang, Huy L. Nguyen, Guanghui Lan

Saturday 17 January

Machine Learning (Statistics) · Cross-listed from cs.LG

Federated Learning for the Design of Parametric Insurance Indices under Heterogeneous Renewable Production Losses

We propose a federated learning framework for the calibration of parametric insurance indices under heterogeneous renewable energy production losses. Producers locally model their losses using Tweedie generalized linear models and private data, while a common index is learned through federated optimization without sharing raw observations. The approach accommodates heterogeneity in variance and link functions and directly minimizes a global deviance objective in a distributed setting. We establish theoretical guarantees under sub-exponential covariate distributions, showing that the Lipschitz constants of the local Tweedie objectives scale as $\frac{1}{\phi_i}$, where $\phi_i$ is the dispersion parameter of producer $i$. This heterogeneity in smoothness causes naive federated averaging to be biased toward producers with stable microclimates — precisely those least in need of basis-risk protection — and motivates the use of corrected aggregation schemes. We implement and compare FedAvg, FedProx and FedOpt, and benchmark them against an existing approximation-based aggregation method. A progressive pool expansion experiment involving up to 121 solar farms in Germany reveals that the approximation-based method becomes entirely non-computable beyond the pool of 50 farms, while federated learning remains valid and actively improves as the pool grows. Federated learning is also over $250\times$ faster than the approximation-based benchmark, establishing it as the only computationally and statistically valid approach for heterogeneous producer pools.
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Statistics Applications · Cross-listed from q-fin.ST

Distributional Fitting and Tail Analysis of Lead-Time Compositions: Nights vs. Revenue on Airbnb

We analyze daily lead-time distributions for two Airbnb demand metrics, Nights Booked (volume) and Gross Booking Value (revenue), treating each day's allocation across 0-365 days as a compositional vector. The data span 2,557 days from January 2019 through December 2025 in a large North American region. Three findings emerge. First, GBV concentrates more heavily in mid-range horizons: beyond 90 days, GBV tail mass typically exceeds Nights by 20-50%, with ratios reaching 75% at the 180-day threshold during peak seasons. Second, Gamma and Weibull distributions fit comparably well under interval-censored cross-entropy. Gamma wins on 61% of days for Nights and 52% for GBV, with Weibull close behind at 38% and 45%. Lognormal rarely wins (<3%). Nonparametric GAMs achieve 18-80x lower CRPS but sacrifice interpretability. Third, generalized Pareto fits suggest bounded tails for both metrics at thresholds below 150 days, though this may partly reflect right-truncation at 365 days; above 150 days, estimates destabilize. Bai-Perron tests with HAC standard errors identify five structural breaks in the Wasserstein distance series, with early breaks coinciding with COVID-19 disruptions. The results show that volume and revenue lead-time shapes diverge systematically, that simple two-parameter distributions capture daily pmfs adequately, and that tail inference requires care near truncation boundaries.
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Statistical Methodology

Using Directed Acyclic Graphs to Illustrate Common Biases in Diagnostic Test Accuracy Studies

Background: Diagnostic test accuracy (DTA) studies, like etiological studies, are susceptible to various biases including reference standard error bias, partial verification bias, spectrum effect, confounding, and bias from misassumption of conditional independence. While directed acyclic graphs (DAGs) are widely used in etiological research to identify and illustrate bias structures, they have not been systematically applied to DTA studies. Methods: We developed DAGs to illustrate the causal structures underlying common biases in DTA studies. For each bias, we present the corresponding DAG structure and demonstrate the parallel with equivalent biases in etiological studies. We use real-world examples to illustrate each bias mechanism. Results: We demonstrate that five major biases in DTA studies can be represented using DAGs with clear structural parallels to etiological studies: reference standard error bias corresponds to exposure misclassification, misassumption of conditional independence creates spurious correlations similar to unmeasured confounding, spectrum effect parallels effect modification, confounding operates through backdoor paths in both settings, and partial verification bias mirrors selection bias. These DAG representations reveal the causal mechanisms underlying each bias and suggest appropriate correction strategies. Conclusions: DAGs provide a valuable framework for understanding bias structures in DTA studies and should complement existing quality assessment tools like STARD and QUADAS-2. We recommend incorporating DAGs during study design to prospectively identify potential biases and during reporting to enhance transparency. DAG construction requires interdisciplinary collaboration and sensitivity analyses under alternative causal structures.
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Statistical Methodology

Lost in Aggregation: The Causal Interpretation of the IV Estimand

Instrumental variable estimation has emerged as a standard approach to mitigating confounding bias in the social sciences and epidemiology, where conducting randomized experiments can be too costly or infeasible. However, justifying the validity of the instrument is frequently challenging. We highlight a problem generally neglected in arguments for instrumental variable validity: the presence of an "aggregate treatment variable", where the treatment (e.g., education, GDP, caloric intake) is composed of finer-grained, unobserved components that each may have a different effect on the outcome. While the aggregation problem itself is general, our focus is on instrumental variable estimation in a linear setting, the regime underlying much of applied IV practice. We show that the causal effect of an aggregate treatment is generally ambiguous, as it depends on how an intervention on the aggregate is instantiated at the component level. We formalize this relation using the aggregate-constrained component intervention distribution (ACID). We then identify two key conditions under which standard instrumental variable estimators identify the aggregate effect. The contrived nature of these conditions implies major limitations on the interpretation of instrumental variable estimates based on aggregate treatments and highlights the need for a broader justificatory base for the exclusion restriction in such settings.
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All authors Danielle Tsao, Krikamol Muandet, Frederick Eberhardt, Emilija Perković

Statistics Applications · Cross-listed from cs.CR

Privacy-Preserving Cohort Analytics for Personalized Health Platforms: A Differentially Private Framework with Stochastic Risk Modeling

Personalized health analytics increasingly rely on population benchmarks to provide contextual insights such as ”How do I compare to others like me?” However, cohort-based aggregation of health data introduces nontrivial privacy risks, particularly in interactive and longitudinal digital platforms. Existing privacy frameworks such as $k$-anonymity and differential privacy provide essential but largely static guarantees that do not fully capture the cumulative, distributional, and tail-dominated nature of re-identification risk in deployed systems. In this work, we present a privacy-preserving cohort analytics framework that combines deterministic cohort constraints, differential privacy mechanisms, and synthetic baseline generation to enable personalized population comparisons while maintaining strong privacy protections. We further introduce a stochastic risk modeling approach that treats re-identification risk as a random variable evolving over time, enabling distributional evaluation through Monte Carlo simulation. Adapting quantitative risk measures from financial mathematics, we define Privacy Loss at Risk (P-VaR) to characterize worst-case privacy outcomes under realistic cohort dynamics and adversary assumptions. We validate our framework through system-level analysis and simulation experiments, demonstrating how privacy-utility tradeoffs can be operationalized for digital health platforms. Our results suggest that stochastic risk modeling complements formal privacy guarantees by providing interpretable, decision-relevant metrics for platform designers, regulators, and clinical informatics stakeholders.
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Statistics Theory

Asymptotic Expansion and Bounds for the Bias of Empirical Tail Value-at-Risk

Tail Value-at-Risk (TVaR) is a widely adopted risk measure playing a critically important role in both academic research and industry practice in insurance. In data applications, TVaR is often estimated using the empirical method, owing to its simplicity and nonparametric nature. The empirical TVaR has been explicitly advocated by regulatory authorities as a standard approach for computing TVaR. However, prior literature has pointed out that the empirical TVaR estimator is negatively biased, which can lead to a systemic underestimation of risk in finite-sample applications. This paper aims to deepen the understanding of the bias of the empirical TVaR estimator in two dimensions: its magnitude as well as the key distributional and structural determinants driving the severity of the bias. To this end, we derive a leading-term approximation for the bias based on its asymptotic expansion. The closed-form expression associated with the leading-term approximation enables us to obtain analytical insights into the structural properties governing the bias of the empirical TVaR estimator. To account for the discrepancy between the leading-term approximation and the true bias, we further derive an explicit upper bound for the bias. We validate the proposed bias analysis framework via simulations and demonstrate its practical relevance using real data.
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Statistical Methodology

Estimations of Extreme CoVaR and CoES under Asymptotic Independence

The two popular systemic risk measures CoVaR (Conditional Value-at-Risk) and CoES (Conditional Expected Shortfall) have recently been receiving growing attention on applications in economics and finance. In this paper, we study the estimations of extreme CoVaR and CoES when the two random variables are asymptotic independent but positively associated. We propose two types of extrapolative approaches: the first relies on intermediate VaR and extrapolates it to extreme CoVaR/CoES via an adjustment factor; the second directly extrapolates the estimated intermediate CoVaR/CoES to the extreme tails. All estimators, including both intermediate and extreme ones, are shown to be asymptotically normal. Finally, we explore the empirical performances of our methods through conducting a series of Monte Carlo simulations and a real data analysis on S&P500 Index with 12 constituent stock data.
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Machine Learning (Statistics)

A Kernel Approach for Semi-implicit Variational Inference

Semi-implicit variational inference (SIVI) enhances the expressiveness of variational families through hierarchical semi-implicit distributions, but the intractability of their densities makes standard ELBO-based optimization biased. Recent score-matching approaches to SIVI (SIVI-SM) address this issue via a minimax formulation, at the expense of an additional lower-level optimization problem. In this paper, we propose kernel semi-implicit variational inference (KSIVI), a principled and tractable alternative that eliminates the lower-level optimization by leveraging kernel methods. We show that when optimizing over a reproducing kernel Hilbert space, the lower-level problem admits an explicit solution, reducing the objective to the kernel Stein discrepancy (KSD). Exploiting the hierarchical structure of semi-implicit distributions, the resulting KSD objective can be efficiently optimized using stochastic gradient methods. We establish optimization guarantees via variance bounds on Monte Carlo gradient estimators and derive statistical generalization bounds of order $\tilde{\mathcal{O}}(1/\sqrt{n})$. We further introduce a multi-layer hierarchical extension that improves expressiveness while preserving tractability. Empirical results on synthetic and real-world Bayesian inference tasks demonstrate the effectiveness of KSIVI.
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All authors Longlin Yu, Ziheng Cheng, Shiyue Zhang, Cheng Zhang

Statistics Applications

A Deep Learning-Copula Framework for Climate-Related Home Insurance Risk

Extreme weather events are becoming more common, with severe storms, floods, and prolonged precipitation affecting communities worldwide. These shifts in climate patterns pose a direct threat to the insurance industry, which faces growing exposure to weather-related damages. As claims linked to extreme weather rise, insurance companies need reliable tools to assess future risks. This is not only essential for setting premiums and maintaining solvency but also for supporting broader disaster preparedness and resilience efforts. In this study, we propose a two-step method to examine the impact of precipitation on home insurance claims. Our approach combines the predictive power of deep neural networks with the flexibility of copula-based multivariate analysis, enabling a more detailed understanding of how precipitation patterns relate to claim dynamics. We demonstrate this methodology through a case study of the Canadian Prairies, using data from 2002 to 2011.
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Statistics Theory · Cross-listed from cs.AI

LIBRA: Language Model Informed Bandit Recourse Algorithm for Personalized Treatment Planning

We introduce a unified framework that seamlessly integrates algorithmic recourse, contextual bandits, and large language models (LLMs) to support sequential decision-making in high-stakes settings such as personalized medicine. We first introduce the recourse bandit problem, where a decision-maker must select both a treatment action and a feasible, minimal modification to mutable patient features. To address this problem, we develop the Generalized Linear Recourse Bandit (GLRB) algorithm. Building on this foundation, we propose LIBRA, a Language Model-Informed Bandit Recourse Algorithm that strategically combines domain knowledge from LLMs with the statistical rigor of bandit learning. LIBRA offers three key guarantees: (i) a warm-start guarantee, showing that LIBRA significantly reduces initial regret when LLM recommendations are near-optimal; (ii) an LLM-effort guarantee, proving that the algorithm consults the LLM only $O(\log^2 T)$ times, where $T$ is the time horizon, ensuring long-term autonomy; and (iii) a robustness guarantee, showing that LIBRA never performs worse than a pure bandit algorithm even when the LLM is unreliable. We further establish matching lower bounds that characterize the fundamental difficulty of the recourse bandit problem and demonstrate the near-optimality of our algorithms. Experiments on synthetic environments and a real hypertension-management case study confirm that GLRB and LIBRA improve regret, treatment quality, and sample efficiency compared with standard contextual bandits and LLM-only benchmarks. Our results highlight the promise of recourse-aware, LLM-assisted bandit algorithms for trustworthy LLM-bandits collaboration in personalized high-stakes decision-making.
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All authors Junyu Cao, Ruijiang Gao, Esmaeil Keyvanshokooh, Jianhao Ma

Statistical Methodology · Cross-listed from cs.LG

Task-tailored Pre-processing: Fair Downstream Supervised Learning

Fairness-aware machine learning has recently attracted various communities to mitigate discrimination against certain societal groups in data-driven tasks. For fair supervised learning, particularly in pre-processing, there have been two main categories: data fairness and task-tailored fairness. The former directly finds an intermediate distribution among the groups, independent of the type of the downstream model, so a learned downstream classification/regression model returns similar predictive scores to individuals inputting the same covariates irrespective of their sensitive attributes. The latter explicitly takes the supervised learning task into account when constructing the pre-processing map. In this work, we study algorithmic fairness for supervised learning and argue that the data fairness approaches impose overly strong regularization from the perspective of the HGR correlation. This motivates us to devise a novel pre-processing approach tailored to supervised learning. We account for the trade-off between fairness and utility in obtaining the pre-processing map. Then we study the behavior of arbitrary downstream supervised models learned on the transformed data to find sufficient conditions to guarantee their fairness improvement and utility preservation. To our knowledge, no prior work in the branch of task-tailored methods has theoretically investigated downstream guarantees when using pre-processed data. We further evaluate our framework through comparison studies based on tabular and image data sets, showing the superiority of our framework which preserves consistent trade-offs among multiple downstream models compared to recent competing models. Particularly for computer vision data, we see our method alters only necessary semantic features related to the central machine learning task to achieve fairness.
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Statistics Applications

Adversarial Drift-Aware Predictive Transfer: Toward Durable Clinical AI

Clinical AI systems frequently suffer performance decay post-deployment due to temporal data shifts, such as evolving populations, diagnostic coding updates (e.g., ICD-9 to ICD-10), and systemic shocks like the COVID-19 pandemic. Addressing this “aging” effect via frequent retraining is often impractical due to computational costs and privacy constraints. To overcome these hurdles, we introduce Adversarial Drift-Aware Predictive Transfer (ADAPT), a novel framework designed to confer durability against temporal drift with minimal retraining. ADAPT innovatively constructs an uncertainty set of plausible future models by combining historical source models and limited current data. By optimizing worst-case performance over this set, it balances current accuracy with robustness against degradation due to future drifts. Crucially, ADAPT requires only summary-level model estimators from historical periods, preserving data privacy and ensuring operational simplicity. Validated on longitudinal suicide risk prediction using electronic health records from Mass General Brigham (2005–2021) and Duke University Health Systems, ADAPT demonstrated superior stability across coding transitions and pandemic-induced shifts. By minimizing annual performance decay without labeling or retraining future data, ADAPT offers a scalable pathway for sustaining reliable AI in high-stakes healthcare environments.
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All authors Xin Xiong, Zijian Guo, Haobo Zhu, Chuan Hong, Jordan W Smoller, Tianxi Cai, Molei Liu