Papers

Topological matter provides natural platforms for robust, non-local information storage, central to quantum error correction. Yet, while the relation between entanglement and topology is well established, little is known about the role of nonstabilizerness (or magic), a pivotal concept in fault-tolerant quantum computation, in topological phases. We introduce the concept of topological magic response, the ability of a state to spread over stabilizer space when perturbed by finite-depth non-Clifford circuits. Unlike a topological invariant or order parameter, this response function probes how a phase reacts to non-Clifford perturbations, revealing the presence of non-local quantum correlations. In Ising-type spin chains, we show that symmetry-broken and paramagnetic phases lack such a response, whereas symmetry-protected topological (SPT) phases always display it. To capture this, we utilize a combination of stabilizer Rényi entropies that, in analogy with topological entanglement entropy, isolates non-locally stored information. Using exact analytic computations and matrix product states simulations based on an algorithmic technique we introduce, we show that SPT phases doped with $T$ gates support robust topological magic response, while trivial phases remain featureless.

Non-relativistic quantum particles in the Earth's gravitational field are successfully described by the Schrödinger equation with Newton's gravitational potential. Particularly, quantum mechanics is in agreement with such experiments as free fall and quantum interference induced by gravity. However, quantum mechanics is a low-energy approximation to quantum field theory. The latter is successful by the description of high-energy experiments. Gravity is embedded in quantum field theory through the general-covariance principle. This framework is known in the literature as quantum field theory in curved spacetime, where the concept of a quantum particle is, though, ambiguous. In this article, we study in this framework how a Hawking particle moves in the far-horizon region of Schwarzschild spacetime by computing its propagator. We find this propagator differs from that which follows from the path-integral formalism – the formalism which adequately describes both free fall and quantum interference induced by gravity.

It is known that quantum field theories in curved spacetime suffer from a number of pathologies, including the inability to relate states on different spatial slices by proper unitary time-evolution operators. In this article, we illustrate this issue by describing the canonical quantisation of a free scalar field in de Sitter space and explicitly demonstrating that the vacuum at a given time slice is unitarily inequivalent to that at any other time. In particular, we find that, if both background and Hamiltonian dynamics are taken into account, this inequivalence holds even for infinitesimally small time steps and not only in the asymptotic time limits.

In this work, we investigate how different reservoir memory profiles influence the dynamical evolution of a single waveguide coupled to an external environment. We compare three representative memory kernels: Lorentzian, Gaussian and Uniform, highlighting their distinct spatial correlations and their impact on system behavior. We compute the transmission amplitude, transparency properties, as well as long-time behavior of the system under each memory model. To quantify deviations from Markovian dynamics, we employ a non-Markovianity measure based on information backflow, allowing a direct comparison between the structured reservoirs and the Markovian limit. Our results reveal clear signatures of memoryless-induced modifications in the transmission spectrum and demonstrate how specific reservoir profiles enhance or suppress non-Markovian effects.

Soon after the dawn of quantum error correction, DiVincenzo and Peres observed that stabilizer codewords could give rise to simple proofs of quantumness via contextuality. This discovery can be recast in the language of nonlocal games: every $n$-qubit stabilizer state defines a specific "stabilizer-testing" $n$-player nonlocal game, which quantum players can win with probability one. If quantum players can moreover outperform all possible classical players, then the state is contextual. However, the classical values of stabilizer-testing games are largely unknown for scalable examples beyond the $n$-qubit GHZ state. We introduce several new methods for upper-bounding the classical values of these games. We first prove a general coding-theory bound for all stabilizer-testing games: if the classical value $p_{\mathrm{cl}}^* < 1$, then $p_{\mathrm{cl}}^* \leq 7/8$, i.e., there is no classical strategy that can perform as well as the optimal quantum strategy even in an asymptotic sense. We then show how to tighten this bound for the most common scalable examples, namely GHZ, toric-code and cyclic cluster states. In particular, we establish an asymptotically tight upper bound for cyclic cluster states using transfer-matrix methods. This leads to the striking conclusion that measuring an exponentially small fidelity to the cyclic cluster state will suffice to witness its contextuality.

Trapped ions as one of the most promising quantum-information-processing platforms, yet conventional entangling gates mediated by collective motion remain slow and difficult to scale. Exciting trapped ions to high-lying electronic Rydberg states provides a promising route to overcome these limitations by enabling strong, long-range dipole-dipole interactions that support much faster multi-qubit operations. Here, we introduce the first scheme for implementing a native controlled-controlled-Z gate with microwave-dressed Rydberg ions by optimizing a single-pulse protocol that accounts for the finite Rydberg-state lifetime. The resulting gate outperforms standard decompositions into one- and two-qubit gates by achieving fidelities above 97% under realistic conditions, with execution times of about 2 microseconds at cryogenic temperatures. To explore the potential of trapped Rydberg ions for fault-tolerant quantum error correction, and to illustrate the utility of three-qubit Rydberg-ion gates in this context, we develop and analyze a proposal for fault-tolerant, measurement-free quantum error correction using the nine-qubit Bacon-Shor code. Our simulations confirm that quantum error correction can be performed in a fully fault-tolerant manner on a linear Rydberg-ion chain despite its limited qubit connectivity. These results establish native multiqubit Rydberg-ion gates as a valuable resource for fast, high-fidelity quantum computing and highlight their potential for fault-tolerant quantum error correction.

The implications of the root singularity of the vacuum polarization tensor near the first pair creation threshold on blackbody radiation are investigated for magnetic fields above the characteristic scale of quantum electrodynamics. We show that the vacuum birefringence in such a strong background leads to an anisotropic behavior of the Planck radiation law. The thermal spectrum is characterized by a resonance that competes with the Wien maximum, causing a crossover in the low $\gamma$-spectrum of the heat radiation. A light state resembling a many-body condensate with slow motion is linked to the high-temperature phase. This novel state of radiation may coexist with nuclear or quark matter in a neutron star's core, increasing its compactness and influencing its stability.

Decay of a four-level diamond scheme via a cascade is a potential source of entangled photon pairs. A solid-state implementation is the biexciton cascade in a semiconductor quantum dot. While high entanglement fidelities have been demonstrated, the two photons, XX and X, are temporally correlated, typically resulting in poor photon coherence. Here, we demonstrate a high two-photon interference visibility (a measure of the photon coherence) for both XX (V=94$\pm$2%) and X (V=82$\pm$6%) photons. This is achieved by Purcell-enhancing the biexciton transition in a low-noise device. We find that the photon coherence follows the well-known quantum optics result upon tuning the XX:X lifetime ratio over two orders of magnitude.

We demonstrate a giant atom by coupling a superconducting transmon qubit to a lithium niobate phononic waveguide at two points separated by about 600 acoustic wavelengths, with a propagation delay of 125 ns. The giant atom yields non-Markovian relaxation dynamics characterized by phonon backflow and a frequency-dependent effective decay rate varying four-fold over merely 4 MHz, corresponding to a Purcell factor exceeding 40. Exploiting this frequency-dependent dissipation, we prepare quantum superposition states with high purity. Our results establish phononic integrated circuits as a versatile platform for giant-atom physics, providing highly tunable quantum devices for advanced quantum information processing.

The recent paper by Sharoglazova et al. reports an energy-dependent parameter $\nu$ extracted from the spatial distribution of photons in a coupled-waveguide experiment. The authors interpret $\nu$ as the speed of quantum particles, even in the classically forbidden regime, and claim that its finite value contradicts the Bohmian mechanics prediction of zero particle velocity. This challenge arises from a fundamental misunderstanding of the operational meaning of v within the Bohmian ontological framework. We demonstrate that v quantifies the spatial gradient of the wavefunctions amplitude, a geometric property of the guiding field, not the kinematical velocity of point-like particles. The experiment therefore does not challenge but rather illustrates the clean ontological separation between the wave and particle aspects inherent to Bohmian mechanics.

This work further develops the calculation of QED effects in a finite Gaussian basis. We focus on the non-linear ${\alpha}(Z{\alpha})^{n\ge 3}$ contribution to the vacuum polarization density, computing the energy shift of 1s$_{1/2}$ states of hydrogen-like ions. Our goal is to improve the numerical computations to achieve a precision comparable to that of Green's function methods reported in the literature. To do so, an analytic expression for the linear contribution to the vacuum polarization density is derived using Riesz projectors. Alternative formulations of the vacuum polarization density and their relation is discussed. The convergence of the finite Gaussian basis scheme is investigated, and the numerical difficulties that arise are characterized. In particular, an error analysis is performed to assess the method's robustness to numerical noise. We then report a strategy for computing the energy shift with sufficient precision to enable a sensible extrapolation of the partial-wave expansion. A key feature of the procedure is the use of even-tempered basis sets, allowing for an extrapolation towards the complete basis set limit.

The variational quantum eigensolver (VQE) is one of the most promising algorithms for low-lying eigenstates calculation on Noisy Intermediate-Scale Quantum (NISQ) computers. Specifically, VQE has achieved great success for ground state calculations of a Hamiltonian. However, excited state calculations arising in quantum chemistry and condensed matter often requires solving more challenging problems than the ground state as these states are generally further away from a mean-field description, and involve less straightforward optimization to avoid the variational collapse to the ground state. Maintaining orthogonality between low-lying eigenstates is a key algorithmic hurdle. In this work, we analyze three VQE models that embed orthogonality constraints through specially designed cost functions, avoiding the need for external enforcement of orthogonality between states. Notably, these formulations possess the desirable property that any local minimum is also a global minimum, helping address optimization difficulties. We conduct rigorous landscape analyses of the models' stationary points and local minimizers, theoretically guaranteeing their favorable properties and providing analytical tools applicable to broader VQE methods. A comprehensive comparison between the three models is also provided, considering their quantum resource requirements and classical optimization complexity.

Measurement-induced phase transitions have largely been explored for projective or continuous measurements of Hermitian observables, assuming perfect detection without information loss. Yet such transitions also arise in more general settings, including quantum-jump processes with non-Hermitian jump operators, and under inefficient detection. A theoretical framework for treating these broader scenarios has been missing. Here we develop a comprehensive replica Keldysh field theory for general quantum-jump processes in both bosonic and fermionic systems. Our formalism provides a unified description of pure-state quantum trajectories under efficient detection and mixed-state dynamics emerging from inefficient monitoring, with deterministic Lindbladian evolution appearing as a limiting case. It thus establishes a direct connection between phase transitions in nonequilibrium steady states of driven open quantum matter and in measurement-induced dynamics. As an application, we study imbalanced and inefficient fermion counting in a one-dimensional lattice system: monitored gain and loss of fermions occurring at different rates, with a fraction of gain and loss jumps undetected. For imbalanced but efficient counting, we recover the qualitative picture of the balanced case: entanglement obeys an area law for any nonzero jump rate, with an extended quantum-critical regime emerging between two parametrically separated length scales. Inefficient detection introduces a finite correlation length beyond which entanglement, as quantified by the fermionic logarithmic negativity, obeys an area law, while the subsystem entropy shows volume-law scaling. Numerical simulations support our analytical findings. Our results offer a general and versatile theoretical foundation for studying measurement-induced phenomena across a wide class of monitored and open quantum systems.

We show that the radial harmonic oscillator problem in the position-dependent mass background of the type $m(\alpha;r) = (1+\alpha r^2)^{-2}$, $\alpha>0$, can be solved by using a point canonical transformation mapping the corresponding Schrödinger equation onto that of the Pöschl-Teller I potential with constant mass. The radial harmonic oscillator problem with position-dependent mass is shown to exhibit a deformed shape invariance property in a deformed supersymmetric framework. The inverse point canonical transformation then provides some exactly-solvable rational extensions of the radial harmonic oscillator with position-dependent mass associated with $X_m$-Jacobi exceptional orthogonal polynomials of type I, II, or III. The extended potentials of type I and II are proved to display deformed shape invariance. The spectrum and wavefunctions of the radial harmonic oscillator potential and its extensions are shown to go over to well-known results when the deforming parameter $\alpha$ goes to zero.

The guided modes supported by dielectric channel waveguides act as individual carriers of momentum. We show this by proving that the modes satisfy an orthogonality condition which relates to the momentum of the optical electromagnetic field, with a link to the more familiar power (energy) orthogonality. This result forms the basis for a rigorous, self-consistent procedure for the quantization of broadband guided electromagnetic fields in the typical channels used in integrated photonic circuits. Our work removes the existing theoretical gap between the classical solution of the Maxwell equations for guided fields and the intuitive understanding of photons in waveguides. The presented approach is valid for straight, lossless, and potentially anisotropic, dielectric waveguides of general shape, in the linear regime, and including material dispersion. Examples for the hybrid modes of a thin film lithium niobate strip waveguide are briefly discussed.

Four decades after Richard Feynman's famous remark, we have reached a stage at which nature can be simulated quantum mechanically. Quantum simulation is among the most promising applications of quantum computing. However, like many quantum algorithms, it is severely constrained by noise in near-term hardware. Quantum-inspired algorithms provide an attractive alternative by avoiding the need for error-prone quantum devices. In this study, we demonstrate that the coherent Ising machine and simulated bifurcation algorithms can accurately reproduce the electronic energy profiles of H_2 and H_2O, capturing their essential energetic features. Notably, we obtain computational times of 1.2 s and 2.4 s for the H_2 and H_2O profiles, respectively, representing a substantial speed-up compared to gate-based quantum computing approaches, which typically require at least 6 s to compute a single molecular geometry with comparable accuracy. These results highlight the potential of quantum-inspired approaches for scaling to larger molecular systems and for future applications in chemistry and materials science.

Laser-induced acoustic desorption (LIAD) enables loading nanoparticles into optical traps under vacuum for levitated optomechanics experiments. Current LIAD systems rely on empirical optimization using available laboratory lasers rather than systematic theoretical design, resulting in large systems incompatible with portable or space-based applications. We develop a theoretical framework using the photoacoustic wave equation to model acoustic wave generation and propagation in metal substrates, enabling systematic optimization of laser parameters. The model identifies key scaling relationships: surface acceleration scales as $\tau^{-2}$ with pulse duration, while acoustic diffraction sets fundamental limits on optimal spot size $w \gtrsim \sqrt{v\tau d}$. Material figures of merit combine thermal expansion and optical absorption properties, suggesting alternatives to traditional aluminum substrates. The framework validates well against experimental data and demonstrates that compact laser systems with sub-nanosecond pulse durations can achieve performance competitive with existing laboratory-scale implementations despite orders-of-magnitude lower pulse energies. This enables rational design of minimal LIAD systems for practical applications.

We propose a quantum circuit design for implementing coined quantum walks on complex networks. In complex networks, the coin and shift operators depend on the varying degrees of the nodes, which makes circuit construction more challenging than for regular networks. To address this issue, we use a dual-register encoding to enable a simplified shift operator and reduces the resource overhead. We implement the circuit using Qmod, a high-level quantum programming language, and evaluated the performance through numerical simulations on Erdős-Rényi, Watts-Strogatz, and Barabási-Albert models. The results show that the circuit depth scales as approximately $N^{1.9}$ regardless of the network topology. Furthermore, we execute the proposed circuits on the ibm\_torino superconducting quantum processor for Watts-Strogatz models with $N=4$ and $N=8$. The experiments show that hardware-aware optimization slightly improved the variation distance and Hellinger fidelity for the larger network, whereas connectivity constraints imposed overhead for the smaller one. These results indicate that while current NISQ devices are limited to small-scale validations, the polynomial scaling of our framework makes it suitable for larger-scale implementations in the fault-tolerant quantum computing era.

Quantum tunnelling, a hallmark phenomenon of quantum mechanics, allows particles to pass through the classically forbidden region. It underpins fundamental processes ranging from nuclear fusion and photosynthesis to the operation of superconducting qubits. Yet the underlying dynamics of particle motion during tunnelling remain subtle and are still the subject of active debate. Here, by analyzing the temporal evolution of the tunnelling process, we show that the particle velocity inside the barrier continuously relaxes from a large initial value toward a smaller one, and may even approach zero in the evanescent regime. Meanwhile, the probability density within the barrier gradually builds up before reaching its stationary profile, in contrast to existing inherently. In addition, starting from the steady-state equations, we derive an explicit relation between the particle velocity and the barrier width, and show that the velocity in evanescent states approaches zero when the barrier is sufficiently wide. These findings resolve the apparent paradox of a vanishing steady-state velocity coexisting with a finite particle density. We point out that defining an effective speed from the probability density, rather than from the probability current, can lead to spuriously nonzero "stationary speed," as appears to be the case in Ref. [Nature 643, 67 (2025)]. Our work establishes a clear dynamical picture for the formation of tunnelling flow and provides a theoretical foundation for testing time-resolved tunnelling phenomena.

We report on a simple and easy to implement method of feedback cooling trapped ions to temperatures below those achievable using only Doppler cooling. Additionally, the feedback cooling results in significantly shorter cooling times. For selected parameters, we demonstrate cooling to temperatures below $\hbar\Gamma/2 k_\mathrm{B}$. The motion of a single ion is monitored in real-time, allowing for the generation of a feedback signal that is applied to an auxiliary trap electrode. Motion detection is implemented by imaging the fluorescence photons emitted by the ion onto a knife edge and detecting the transmitted light, a method used so far to cool trapped nanoparticles. The intensity modulation of the fluorescence resulting from the ion motion is used to generate and apply the feedback signal and also to determine the ion temperature. While the method benefits from a high rate of detected scattered photons, which can be a challenge, and which we address by using a parabolic mirror for collecting the fluorescence, we expect the method to also be applicable when using lenses with moderate numerical apertures.

We investigate entropy of electron-positron pair production in time-dependent Sauter pulse electric field. Both cases of pair longitudinal momentum only and full momentum consideration are examined. We further examine three types of entropy, one is the usual entanglement entropy $S_{\text{E}}$, the other two extensions are thermal distribution entropy $S_{\text{Th}}$, and that with the chemical potential correction, $S_{\text{Th,CP}}$. For short pulse, $S_{\text{E}}$ is higher than $S_{\text{Th}}$ and vice versa for long pulse. The chemical potential causes the single-particle average thermal distribution entropy $\frac{S_{\text{Th,CP}}}{N}$ to exhibit non-monotonic behavior, similar to the single-particle average entanglement entropy $\frac{S_{\text{E}}}{N}$ in the short-pulse range. In the full momentum case, we calculate the thermal distribution entropy $S_{\text{Th, U}}$ via introducing the Unruh temperature as the local effective temperature. We find that both $S_{\text{Th, U}}$ and $S_{\text{E}}$ saturate asymptotically to the constant while the former has a larger asymptotic value. The results presented in this study reveals that the different entropies have some delicate relationships among them.

In this work, we revisit prefix sums through the lens of linear algebra. We describe an identity that decomposes triangular all-ones matrices as a sum of two Kronecker products, and apply it to design recursive prefix sum algorithms and circuits. Notably, the proposed family of circuits is the first one that achieves the following three properties simultaneously: (i) zero-deficiency, (ii) constant fan-out per-level, and (iii) depth that is asymptotically strictly smaller than $2\log(n)$ for input length $n$. As an application, we show how to use these circuits to design quantum adders with $1.893\log(n)+O(1)$ Toffoli depth, $O(n)$ Toffoli gates, and $O(n)$ additional qubits, improving the Toffoli depth and/or Toffoli size of existing constructions.

In a quantum field approach to neutrino oscillations, the neutrino is treated as a propagator, while the external initial and final particle states are described by covariant wave packets. For the asymptotic behavior on short and long macroscopic baselines, the wave packet modified neutrino propagator is expressed through asymptotic series in powers of dimensionless Lorentz and rotation invariant variables. In both regimes, leading-order corrections violate the classical inverse-square law and lead to a decrease in the neutrino-induced event rate. The possibility that the so-called reactor antineutrino anomaly can, at least partially, be explained within this approach is discussed.

The accelerating global development of quantum technologies strengthens the case for introducing quantum computing concepts before university. Yet in Latin America, there is no consolidated, region wide integration of quantum computing into secondary education, and the feasibility conditions for doing so remain largely unexamined. This paper proposes a qualitative, comparative framework to assess academic readiness for quantum education across six countries - Peru, Bolivia, Chile, Argentina, Brazil, and Colombia - grounded in the relationship between curriculum compatibility and enabling conditions spanning institutional capacity, teacher preparation, infrastructure, and equity. Using official curricula, policy documents, national statistics, and educational reports, we apply structured qualitative coding and a 1-5 ordinal scoring system to generate a cross country diagnosis. The findings reveal substantial regional asymmetries: among the six countries studied, Chile emerges as the most institutionally prepared for progressive quantum education integration, while the remaining countries exhibit varying combinations of curricular gaps and fragmented but promising enabling conditions. Building on this diagnosis, we propose a country sensitive, regionally coordinated roadmap for staged implementation, beginning with teacher development and pilot centers, leveraging open source platforms and local language resources, and scaling toward gradual curricular integration. This work establishes a baseline for future quantitative and mixed method studies evaluating learning outcomes, motivation, and scalable models for quantum education in Latin America.

Nonlocality can be witnessed either through Bell-inequality violations or through logical contradictions such as Hardy's paradox. In the bipartite two input two outcome scenario, these two routes have distinct geometric behavior: CHSH-maximal correlations are exposed points of the quantum set, whereas known Hardy-type self-testing correlations on the no-signaling boundary are non-exposed. Here we show that this bipartite intuition fails in the tripartite two input two outcome scenario. We study the tripartite instance of a multipartite Hardy-type paradox and prove that the correlation attaining the maximal Hardy success probability self-tests the Greenberger–Horne–Zeilinger state and the associated measurements. Although this correlation lies on the no-signaling boundary, we show that it is an extremal and exposed point of the quantum correlation set. Moreover, it coincides with the correlation attaining the maximal violation of the Mermin inequality. Thus, in the tripartite GHZ scenario, the logical-paradox and Bell-inequality routes to nonlocality select the same exposed quantum boundary point. We also establish a robust version of the self-test, showing that small deviations from the ideal Hardy constraints imply quantitative closeness to the target state and measurements. Our results reveal a qualitative geometric difference between bipartite and tripartite Hardy-type nonlocality and suggest a broader investigation of exposedness for multipartite Hardy correlations in the multiparty setting.

Parametric amplification offers a powerful means to enhance quantum interactions through field squeezing, yet it typically introduces additional noise which accelerates quantum decoherence, a major obstacle for scalable quantum information processing. The squeezing field is implemented in cavities rather than continuous waveguides, thereby limiting its scalability for applications in quantum simulation. Giant atoms, which couple to waveguides at multiple points, provide a promising route to mitigate dissipation via engineered interference, enabling decoherence-free interactions. We extend the squeezing-amplified interaction to a novel quantum platform combining giant atoms with traveling-wave parametric waveguides based on $\chi^{(2)}$ nonlinearity. By exploiting destructive interference between different coupling points, the interaction between giant atoms is not only significantly enhanced but also becomes immune to squeezed noise. Unlike conventional waveguide quantum electrodynamics without a squeezing pump, the giant emitters exhibit both exchange and pairing interactions, making this platform particularly suitable for simulating many-body quantum physics. More intriguingly, the strengths of these interactions can be smoothly tuned by adjusting the squeezing and coupling parameters. Our architecture thus provides a versatile and scalable platform for quantum simulation of strongly correlated physics and paves the way toward robust quantum control in many-body regimes.

Color centers hosted in hexagonal boron nitride have emerged as a highly promising platform for single-photon emission and spin-photon technologies relevant to quantum communication and quantum networking. As a wide-bandgap van der Waals material, hBN can host optically active quantum defects across a broad spectral range. Here, we demonstrate a simple and scalable oxygen-plasma process that reproducibly creates single quantum emitters in hBN with blinking-free zero-phonon lines spanning the near-infrared from 700 up to 971 nm. These emitters combine MHz-level brightness, single-photon purity up to 99.9%, and ultranarrow cryogenic linewidths down to 2.7~GHz under quasi-resonant excitation, placing them in a particularly attractive regime for quantum photonics. Photostability measurements further reveal resistance to photobleaching, sub-nm spectral stability over long timescales, and near-shot-noise-limited intensity fluctuations. Analysis of the phonon sidebands shows weak vibronic coupling and ZPL-dominated emission, with Debye–Waller factors approaching 50%. Control experiments together with EDS elemental mapping support oxygen incorporation as a necessary ingredient in activating the NIR emitter population, while first-principles calculations identify O$_N$V$_N$ and O$_N$V$_N$H as the leading defect candidates. These results establish a high-performance NIR quantum-emitter platform in hBN for free-space quantum networking and future integrated quantum-photonic architectures.

Effective molecular representations are essential for ligand-based virtual screening. We investigate how quantum data embedding strategies can improve this task by developing and evaluating a family of quantum-classical hybrid embedding approaches. These approaches combine classical neural networks with parameterized quantum circuits in different ways to generate expressive molecular representations and are assessed across two benchmark datasets of different sizes: the LIT-PCBA and COVID-19 collections. Across multiple biological targets and class-imbalance settings, several quantum and hybrid embedding variants consistently outperform classical baselines, especially in limited-data regimes. These results highlight the potential of optimized quantum data embeddings as data-efficient tools for ligand-based virtual screening.

Nelson's stochastic mechanics formulates quantum dynamics as a real-time conservative diffusion process in which a particle undergoes Brownian-like motion with a fluctuation amplitude fixed by Planck's constant. While being mathematically equivalent to the Schrödinger formulation, this approach provides an alternative dynamical framework that enables the study of time-resolved quantities that are not straightforwardly defined within the standard operator-based approach. In the present work, Nelson's stochastic mechanics is employed to investigate tunneling-time statistics for bound states in double-well potentials. Using first-passage time theory within this framework, both the mean tunneling time, $\bar{\tau}$, and the full probability distribution, $p({\tau})$, are computed. The theoretical predictions are validated through extensive numerical simulations of stochastic trajectories for two representative potentials. For the square double-well potential, analytical expressions for $\bar{\tau}$ are derived and are shown to be in excellent agreement with simulations. In the high-barrier limit, the results reveal a direct relation between the stochastic-mechanical and quantum-mechanical tunneling times, expressed as $\tau_{\mathrm{QM}} = (\pi/2)\bar{\tau}$, where $\tau_{\mathrm{QM}}$ corresponds to half the oscillation period of the probability of finding the particle in either well. This relation is further confirmed for generic double-well systems through a WKB analysis. As a concrete application, the inversion dynamics of the ammonia molecule is analyzed, yielding an inversion frequency of approximately 24 GHz, in close agreement with experimental observations. These results highlight the potential of stochastic mechanics as a conceptually coherent and quantitatively consistent framework for analyzing tunneling phenomena in quantum systems.

I present a first-quantization deterministic algorithm for antisymmetrizing a spatially separated target-projectile system containing $N_T$ and $N_p$ identical fermions, respectively. The method constructs a fully antisymmetric wavefunction from the product of two independently antisymmetrized many-body states, each of which may be a superposition of Slater determinants. The algorithm uses a Dicke-state ancilla register that coherently encodes all one-particle exchange channels between the two subsystems, and, crucially, requires only single-particle swaps to generate the full antisymmetric structure. A total of $O(N_T N_p)$ single-particle exchanges are needed, with up to $N_p$ of them implemented in parallel, if an additional $N_p$ ancillae are used. The correct fermionic phase is incorporated through application of $Z$ gates on $N_T$ ancillae, after which the ancilla register is efficiently uncomputed using a compact sequence of controlled operations. This construction provides a nontrivial and scalable protocol for preparing fully antisymmetric states in reaction and scattering simulations, significantly expanding the range of systems that can be addressed with first-quantized quantum algorithms.